Details of the Drug

General Information of Drug (ID: DM8I94Y)

Drug Name
Venetoclax
Synonyms Venclexta
Indication
Disease Entry ICD 11 Status REF
Chronic lymphocytic leukaemia 2A82.0 Approved [1]
Affected Organisms
Humans and other mammals
ATC Code
L01XX52: Venetoclax
L01XX: Other antineoplastic agents
L01X: OTHER ANTINEOPLASTIC AGENTS
L01: ANTINEOPLASTIC AGENTS
L: ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
Drug Type
Small molecular drug
Structure
3D MOL 2D MOL
#Ro5 Violations (Lipinski):
3		 Molecular Weight 868.447
Logarithm of the Partition Coefficient Not Available
Rotatable Bond Count 12
Hydrogen Bond Donor Count 3
Hydrogen Bond Acceptor Count 11
ADMET Property
Absorption AUC
The area under the plot of plasma concentration (AUC) of drug is 32.8 +/- 16.9 mgh/L [2]
Absorption Cmax
The maximum plasma concentration (Cmax) of drug is 2.1 +/- 1.1 mg/L [2]
Absorption Tmax
The time to maximum plasma concentration (Tmax) is 5-8 h [2]
Clearance
The drug is mainly cleared by the liver []
Elimination
After single oral administration of 200 mg radiolabeled [14C]-venetoclax dose to healthy subjects, >99.9% of the dose was found in feces and <0.1% of the dose was excreted in urine within 9 days, suggesting that hepatic elimination is responsible for the clearance of venetoclax from systemic circulation []
Half-life
The concentration or amount of drug in body reduced by one-half in 19 - 26 hours [3]
Metabolism
The drug is metabolized via the CYP3A4/5 [4]
Vd
The volume of distribution (Vd) of drug is 256-321 L []
Chemical Identifiers
Formula
C45H50ClN7O7S
IUPAC Name
4-[4-[[2-(4-chlorophenyl)-4,4-dimethylcyclohexen-1-yl]methyl]piperazin-1-yl]-N-[3-nitro-4-(oxan-4-ylmethylamino)phenyl]sulfonyl-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide
Canonical SMILES
CC1(CCC(=C(C1)C2=CC=C(C=C2)Cl)CN3CCN(CC3)C4=CC(=C(C=C4)C(=O)NS(=O)(=O)C5=CC(=C(C=C5)NCC6CCOCC6)[N+](=O)[O-])OC7=CN=C8C(=C7)C=CN8)C
InChI
InChI=1S/C45H50ClN7O7S/c1-45(2)15-11-33(39(26-45)31-3-5-34(46)6-4-31)29-51-17-19-52(20-18-51)35-7-9-38(42(24-35)60-36-23-32-12-16-47-43(32)49-28-36)44(54)50-61(57,58)37-8-10-40(41(25-37)53(55)56)48-27-30-13-21-59-22-14-30/h3-10,12,16,23-25,28,30,48H,11,13-15,17-22,26-27,29H2,1-2H3,(H,47,49)(H,50,54)
InChIKey
LQBVNQSMGBZMKD-UHFFFAOYSA-N
Cross-matching ID
PubChem CID
49846579
ChEBI ID
CHEBI:133021
CAS Number
1257044-40-8
UNII
N54AIC43PW
DrugBank ID
DB11581
VARIDT ID
DR00008
Combinatorial Drugs (CBD) Click to Jump to the Detailed CBD Information of This Drug

Molecular Interaction Atlas of This Drug


Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [5]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Apoptosis regulator BAX (BAX) OTAW0V4V BAX_HUMAN Protein Interaction/Cellular Processes [6]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Gene/Protein Processing [7]
Bcl-2 homologous antagonist/killer (BAK1) OTDP6ILW BAK_HUMAN Protein Interaction/Cellular Processes [6]
Bcl-2-binding component 3, isoforms 3/4 (BBC3) OTUAXDAY BBC3B_HUMAN Drug Response [8]
Bcl-2-like protein 1 (BCL2L1) OTRC5K9O B2CL1_HUMAN Gene/Protein Processing [6]
Broad substrate specificity ATP-binding cassette transporter ABCG2 (ABCG2) OTW8V2V1 ABCG2_HUMAN Protein Interaction/Cellular Processes [9]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Protein Interaction/Cellular Processes [10]
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) OT2YYI1A MCL1_HUMAN Gene/Protein Processing [11]
Phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1) OTXEE550 APR_HUMAN Gene/Protein Processing [6]
Poly polymerase 1 (PARP1) OT310QSG PARP1_HUMAN Protein Interaction/Cellular Processes [10]
Molecular Interaction Atlas (MIA) Jump to Detail Molecular Interaction Atlas of This Drug

Experimental Cancer Drug Sensitivity Information

Cancer Drug Sensitivity Data Curated from 43 Cell Line(s) in Bone Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
RPMI-3460/CS1 GDSC2 1.4919 3.8005 -0.8482 2.2825
CADO-ES1 GDSC2 -0.3265 8.7452 -4.6476 26.5588
EW-3 GDSC2 -0.2885 10.1977 -5.3412 28.7427
EW-22 GDSC2 0.8008 4.6951 -1.7182 8.7196
EW-12 GDSC2 0.9759 3.0843 -0.8246 2.9726
ES1 GDSC2 1.0487 3.2625 -0.8622 3.0579
NOS-1 [Human HNSCC] GDSC2 1.0559 6.4062 -2.3714 11.9461
EW-24 GDSC2 1.1328 2.6604 -0.5469 1.2491
SK-PN-DW GDSC2 1.1554 3.9738 -1.1263 4.3864
ES8 GDSC2 1.178 4.2872 -1.2593 5.1228
EW-1 GDSC2 1.2082 4.0239 -1.1163 4.2282
ES5 GDSC2 1.2151 10.3336 -4.1924 20.49
CHSA8926 GDSC2 1.3135 5.1037 -1.5576 6.6084
CAL-72 GDSC2 1.3631 5.9471 -1.9285 8.6782
CHSA0108 GDSC2 1.4527 4.2857 -1.0873 3.6303
EW-11 GDSC2 1.4674 8.7638 -3.2273 15.4938
EW-7 GDSC2 1.5102 4.2339 -1.0301 3.2214
EW-13 GDSC2 1.5447 10.3914 -3.9712 18.7412
TC-71 GDSC2 1.5558 7.6399 -2.6138 12.1063
A-673 GDSC2 1.5729 3.6423 -0.7375 1.6301
ES6 GDSC2 1.606 5.6376 -1.6191 6.3807
U2OS GDSC2 1.6391 6.7879 -2.1442 9.3193
ES7 GDSC2 1.6478 4.494 -1.0678 3.2099
HuO9 GDSC2 1.662 11.4705 -4.4159 20.2882
EW-18 GDSC2 1.9515 5.5614 -1.3719 4.3757
CHSA0011 GDSC2 1.9682 4.7744 -1.0152 2.4858
HuO-3N1 GDSC2 2.0288 4.9241 -1.0476 2.568
NY GDSC2 2.067 6.0415 -1.5215 5.0017
U-CH2 GDSC2 2.0845 3.7451 -0.5475 0.4663
H-EMC-SS GDSC2 2.0914 4.8454 -0.9817 2.1716
ES4 GDSC2 2.1329 4.8789 -0.9748 2.0906
EW-16 GDSC2 2.1602 5.4087 -1.187 3.0909
SK-ES-1 GDSC2; CTRP2 3.8598 6.3883 3.5583 14.6488
MHH-ES-1 GDSC2 4.4041 13.7734 -3.6542 11.5845
SaOS-2 GDSC2; CTRP2 4.648 7.9546 3.7712 11.8535
Hs 888.T CTRP2 6.2281 7.8764 5.2766 2.8897
SK-N-MC CTRP2 6.6276 11.4547 3.8086 8.3186
Hs 822.T CTRP2 7.5593 8.3995 5.7757 0.048
SJSA-1 GDSC2; CTRP2 8.0825 9.9089 5.4332 0.4289
HOS GDSC2; CTRP2 8.1808 13.9906 3.6796 6.0713
CAL-78 GDSC2; CTRP2 8.3011 10.0458 5.4712 0.281
G-292 clone A141B1 GDSC2; CTRP2 10.2306 19.0495 2.611 7.4051
MG-63 GDSC2; CTRP2 13.4594 28.0131 0.4517 10.5011
⏷ Show the Full List of 43 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 196 Cell Line(s) in Haematopoietic And Lymphoid Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
JK1 CTRP2 8.3547 10.8609 5.1809 0.9418
JM1 GDSC2; CTRP2 -4.5018 1.3888 -4.6047 64.1481
KO52 CTRP2 -10.1289 0.3802 -10.4436 82.618
MV4-11 GDSC2 -9.4446 -7.0739 -9.4449 89.5733
LC4-1 GDSC2 -9.3938 -6.4878 -9.396 87.6383
SUP-B15 GDSC2; CTRP2 -9.1359 -4.971 -9.1371 88.9265
SUP-HD1 GDSC2; CTRP2 -8.9196 2.4983 -9.4727 75.8456
EoL-1 GDSC2; CTRP2 -8.7326 -5.4283 -8.7328 88.8729
MHH-CALL-2 GDSC2 -8.435 -6.3546 -8.4353 82.9253
Ri-1 CTRP2 -8.2999 -3.0022 -8.3124 86.537
MOLM-13 GDSC2 -8.2339 -5.4132 -8.2381 79.6755
NU-DHL-1 CTRP2 -8.2326 -4.8283 -8.2329 90.1178
ME1 GDSC2 -7.7479 -5.812 -7.7482 77.066
SK-MM-2 GDSC2; CTRP2 -7.6432 -2.8944 -7.6509 81.5547
SEM CTRP2 -7.6104 -4.6309 -7.6105 88.1395
KY821 GDSC2 -7.5715 -2.1292 -7.7941 69.1088
OCI-AML-2 GDSC2 -7.409 -2.2261 -7.6047 68.453
BALL-1 GDSC2 -7.4009 -4.9446 -7.4039 73.2056
ROS-50 GDSC2 -7.1605 -5.3941 -7.1607 71.6146
RS4;11 GDSC2; CTRP2 -7.1397 -3.9591 -7.1401 81.1525
MY-M12 GDSC2 -7.0471 -4.2623 -7.0568 69.5545
Kasumi-1 GDSC2; CTRP2 -6.9972 1.6178 -7.2693 72.906
OCI-Ly7 GDSC2 -6.848 -4.8123 -6.8491 68.4096
SU-DHL-16 GDSC2 -6.8308 -4.4532 -6.8348 67.9841
ME1 CTRP2 -6.5633 112.2173 -57.8831 52.3542
Kasumi-2 CTRP2 -6.4808 -5.1926 -6.4808 83.3885
HL-60 GDSC2 -6.3694 -1.3585 -6.6329 60.9783
ALL-PO GDSC2 -6.1637 1.9941 -7.3601 56.9034
697 GDSC2; CTRP2 -6.0755 0.1059 -6.1502 72.0052
Karpas-231 GDSC2 -5.9954 -2.6287 -6.0554 59.3571
Loucy GDSC2 -5.9451 -1.7335 -6.1103 58.2784
KMS-12-BM GDSC2 -5.8671 -2.9597 -5.8981 58.4466
Granta-519 GDSC2; CTRP2 -5.8202 4.275 -6.4671 66.4283
RL GDSC2; CTRP2 -5.6292 -1.2669 -5.6402 71.6283
OCI-Ly19 GDSC2; CTRP2 -5.4939 0.5401 -5.575 69.2526
DB GDSC2 -5.454 -2.5229 -5.498 54.5069
VAL GDSC2 -5.1446 -3.142 -5.151 51.6124
ML-2 GDSC2 -4.6996 -2.3739 -4.7243 47.2124
NU-DUL-1 GDSC2; CTRP2 -4.6413 -3.1745 -4.6413 66.745
DoHH2 GDSC2 -4.4472 1.1282 -5.2024 45.9569
ALL-SIL GDSC2 -4.1616 2.7019 -5.4855 44.5589
BV-173 GDSC2; CTRP2 -4.0087 5.5329 -4.7915 59.2169
BONNA-12 GDSC2 -3.9634 10.514 -8.8393 46.3141
TK [Human B-cell lymphoma] GDSC2 -3.7995 -1.0538 -3.9136 38.6238
OCI-Ly3 CTRP2 -3.736 9.2228 -5.6395 58.4525
KOPN-8 GDSC2 -3.6942 2.0227 -4.7204 40.4798
WSU-DLCL2 GDSC2 -3.4806 8.1262 -7.2334 43.4119
NKM-1 GDSC2 -3.1481 4.2917 -5.1182 38.6348
MOLT-16 GDSC2; CTRP2 -3.1464 4.2006 -3.5493 56.1497
HAL-01 GDSC2 -2.4737 1.3048 -3.1416 28.2785
SU-DHL-4 GDSC2; CTRP2 -2.3287 6.4466 -3.2064 51.7541
KG-1 GDSC2 -1.9261 12.1119 -7.7275 38.7955
MHH-CALL-4 GDSC2; CTRP2 -1.8665 4.4435 -2.2106 49.4822
MOLM-6 CTRP2 -1.8342 6.7691 -2.7621 51.8496
NALM-6 GDSC2 -1.1921 8.514 -5.2872 31.4095
P31/FUJ GDSC2 -0.5716 9.2732 -5.1212 28.9141
WSU-NHL GDSC2 -0.3222 9.9991 -5.2705 28.6252
ATN-1 GDSC2 0.079 9.0966 -4.4826 24.735
CESS GDSC2 0.0933 6.7318 -3.2885 19.4843
OCI-AML-3 GDSC2 0.266 6.124 -2.8432 16.673
KE-37 GDSC2 0.3818 7.5352 -3.4543 19.4525
HDLM-2 GDSC2 0.391 10.4319 -4.8938 25.3419
JVM-2 GDSC2 0.3949 22.4404 -10.8928 37.1581
P30/OHK GDSC2 0.3951 4.0286 -1.6952 9.6067
IM-9 GDSC2 0.4152 6.5765 -2.949 16.8127
MHH-CALL-3 CTRP2 0.4803 15.3065 -3.7679 43.5018
EB2 GDSC2 0.4988 2.4585 -0.8425 4.0468
HH [Human lymphoma] GDSC2 0.556 4.2385 -1.6756 9.0667
SUP-M2 GDSC2 0.5848 4.2298 -1.6495 8.8335
NK-92MI GDSC2 0.5907 4.4294 -1.7438 9.3963
Karpas-1106P GDSC2 0.6401 3.2457 -1.1253 5.4636
DEL GDSC2 0.6841 3.4287 -1.1831 5.7181
P12-Ichikawa GDSC2 0.6965 5.274 -2.0814 11.162
VL51 GDSC2 0.7269 14.1401 -6.4738 29.1213
L-540 GDSC2; CTRP2 0.7285 4.7845 0.5321 33.7993
NCI-H929 GDSC2 0.7951 7.3028 -3.0118 16.1036
BL-41 GDSC2 0.8116 3.2141 -0.9914 4.2719
ARH-77 GDSC2 0.8282 8.5005 -3.5813 18.8211
KMOE-2 GDSC2 0.8439 6.7822 -2.716 14.4012
HC-1 GDSC2 0.8664 3.7803 -1.2259 5.5716
MOLT-4 GDSC2 0.9034 9.8849 -4.2112 21.3736
SUP-B8 GDSC2 0.9053 3.4454 -1.0392 4.3654
A4/Fukuda GDSC2 0.9351 3.7348 -1.1573 5.011
Jurkat GDSC2 0.9542 5.0371 -1.7744 8.6935
A3/Kawakami GDSC2 0.9616 5.611 -2.05 10.3162
BC-3 GDSC2 0.9774 5.4379 -1.9536 9.7084
RPMI-8402 GDSC2 0.9872 5.7697 -2.1092 10.6012
Jiyoye GDSC2 1.0102 3.3785 -0.9399 3.5751
ST486 GDSC2 1.033 3.4831 -0.9743 3.7322
GDM-1 GDSC2; CTRP2 1.034 9.6543 -0.7048 35.8821
RC-K8 GDSC2 1.0372 3.2958 -0.8846 3.2062
Farage GDSC2 1.0405 2.7915 -0.6536 1.9175
P32/ISH GDSC2 1.1243 6.6286 -2.4304 12.1131
DND-41 GDSC2 1.1292 3.1415 -0.7594 2.3503
Namalwa GDSC2 1.1896 6.4114 -2.2765 11.0838
MLMA GDSC2 1.1942 3.3114 -0.7982 2.459
HT GDSC2 1.2099 7.5984 -2.844 14.1619
SIG-M5 GDSC2 1.2329 2.2696 -0.3441 0.3351
SU-DHL-1 GDSC2 1.2486 11.0266 -4.5104 21.6708
EM-2 GDSC2 1.2644 3.4123 -0.8033 2.3781
AML-193 CTRP2 1.2988 4.7065 1.1598 32.0754
CCRF-CEM GDSC2 1.3056 3.4415 -0.7931 2.2625
CML-T1 GDSC2 1.3452 3.0609 -0.608 1.2875
JSC-1 GDSC2 1.3914 6.1825 -2.0225 9.1616
Ku812 GDSC2 1.4013 5.2697 -1.5784 6.5508
MN-60 GDSC2 1.4312 6.5585 -2.1766 9.9579
SU-DHL-6 GDSC2; CTRP2 1.4509 10.9377 -0.8152 34.8364
YT GDSC2 1.4675 3.0559 -0.5471 0.8951
L-1236 GDSC2 1.4986 4.9199 -1.3515 5.0452
MOLT-13 GDSC2; CTRP2 1.5043 25.7508 -7.8082 42.5318
SCC-3 GDSC2 1.5121 3.1088 -0.5477 0.8578
K-562 GDSC2 1.5219 3.2277 -0.591 1.0264
Daudi GDSC2 1.5739 3.199 -0.5554 0.835
OPM-2 GDSC2 1.585 10.2868 -3.8897 18.2902
BE-13 GDSC2 1.6081 6.7588 -2.1513 9.426
WIL2 NS GDSC2 1.6098 3.4846 -0.6537 1.2083
Hs 445 GDSC2 1.6158 11.1997 -4.3169 20.0055
GR-ST GDSC2 1.6158 4.3343 -1.0148 2.9755
Karpas-45 GDSC2 1.6382 7.3631 -2.4218 10.8723
U-698-M GDSC2 1.7362 3.4985 -0.6007 0.8747
LAMA-84 GDSC2 1.7442 3.6803 -0.6696 1.1443
Ramos.2G6.4C10 GDSC2 1.7505 7.5586 -2.4387 10.7184
TALL-1 [Human adult T-ALL] GDSC2; CTRP2 1.7559 5.8401 1.4184 27.8679
THP-1 GDSC2; CTRP2 1.8138 6.8834 1.1738 28.4755
JVM-3 GDSC2 1.8619 3.9195 -0.7111 1.2061
QIMR-WIL GDSC2 1.8763 20.5981 -8.7802 31.3494
GA-10 GDSC2 1.8915 3.7659 -0.6365 0.885
CRO-AP2 GDSC2 1.9077 7.7227 -2.4105 10.2282
MEG-01 GDSC2 1.9225 4.3362 -0.8529 1.7658
TUR GDSC2 1.9451 3.5857 -0.5447 0.5343
HEL GDSC2 1.9642 3.4744 -0.4959 0.3849
PF-382 GDSC2 2.0864 4.6653 -0.9088 1.8393
CA46 GDSC2 2.0995 4.5809 -0.8675 1.6408
MHH-PREB-1 GDSC2 2.1203 3.779 -0.5457 0.4435
DG-75 GDSC2 2.1426 5.5557 -1.2609 3.4938
CTV-1 GDSC2 2.2042 3.626 -0.4592 0.2118
CTB-1 GDSC2 2.3312 4.5163 -0.7359 0.9142
KCL-22 GDSC2 2.3516 4.4284 -0.6936 0.757
H9 GDSC2 2.3824 4.6889 -0.7805 1.0361
KM-H2 GDSC2 2.4628 4.1824 -0.5591 0.3305
PL-21 GDSC2 2.4647 4.9574 -0.8492 1.2275
BC-1 GDSC2 2.6127 4.276 -0.5366 0.2371
U-937 CTRP2 2.8851 7.8724 1.969 24.3234
RCH-ACV GDSC2; CTRP2 3.1254 10.9557 0.8726 25.8047
SU-DHL-5 GDSC2 4.0387 17.5613 -5.6853 19.7699
SET-2 CTRP2 4.0388 5.4201 3.9891 13.5303
Mono-Mac-6 GDSC2; CTRP2 4.1848 17.3495 -1.224 28.8264
KMS-11 GDSC2; CTRP2 4.5468 14.8138 0.3566 24.0024
KMS-34 CTRP2 4.6474 14.1819 0.7599 23.8365
Toledo CTRP2 5.8803 14.4031 1.7275 17.9081
HuT 78 CTRP2 6.048 11.3527 3.3932 11.105
OCI-Ly10 CTRP2 6.332 28.1181 -4.7537 32.0387
L-428 GDSC2; CTRP2 6.495 12.5941 3.1371 10.622
MOLM-16 GDSC2; CTRP2 6.7502 13.1374 3.0675 10.4575
KMS-28BM CTRP2 6.8611 28.8903 -4.7053 31.1072
OCI-M1 GDSC2; CTRP2 6.9222 12.7951 3.3698 9.0251
Reh GDSC2; CTRP2 6.9988 19.1632 0.2624 19.5392
MC116 GDSC2; CTRP2 7.0289 8.9569 5.3039 1.5449
Ci-1 CTRP2 7.1748 7.8473 5.8284 0.0501
M-07e CTRP2 7.2247 17.4946 1.2707 16.9401
MOLP-2 CTRP2 7.4113 15.8017 2.2528 13.1393
Karpas-422 GDSC2; CTRP2 7.4646 19.9585 0.2326 18.8408
Raji GDSC2; CTRP2 7.4723 10.4036 4.9086 2.4567
KYO-1 CTRP2 7.5307 13.0491 3.69 7.3457
SU-DHL-10 GDSC2; CTRP2 7.6011 8.5143 5.7514 0.0606
RPMI-8226 GDSC2; CTRP2 7.6271 9.7352 5.2913 1.0532
MM1.S GDSC2; CTRP2 7.7259 9.1593 5.5679 0.2984
AMO1 GDSC2; CTRP2 7.7735 8.7419 5.7346 0.0539
NOMO-1 GDSC2; CTRP2 7.8598 9.199 5.6066 0.1888
SKM-1 GDSC2; CTRP2 7.8636 8.9603 5.692 0.0804
LP-1 GDSC2; CTRP2 7.8675 15.8664 2.5574 10.6045
SU-DHL-8 GDSC2; CTRP2 7.8749 9.178 5.6199 0.1654
P3HR-1 CTRP2 7.9123 9.2024 5.6253 0.1592
F-36P CTRP2 8.0096 10.5314 5.1497 1.2686
CMK CTRP2 8.0985 9.0927 5.7283 0.032
SUP-T11 CTRP2 8.1099 9.8449 5.4687 0.3712
OCI-AML-5 CTRP2 8.1142 22.054 -0.3077 20.192
L-363 GDSC2; CTRP2 8.1524 9.3291 5.668 0.0647
SR GDSC2; CTRP2 8.1707 9.6719 5.5558 0.1858
Karpas-299 GDSC2; CTRP2 8.275 10.3083 5.3623 0.497
U266B1 GDSC2; CTRP2 8.2852 10.3032 5.3686 0.4795
SUP-T1 GDSC2; CTRP2 8.4191 10.2086 5.4581 0.2683
Mono-Mac-1 CTRP2 8.4805 23.5774 -0.7839 20.8519
MOLP-8 GDSC2; CTRP2 8.5134 9.924 5.5926 0.0848
REC-1 CTRP2 8.7174 10.5964 5.4331 0.2448
MOTN-1 CTRP2 9.3022 23.5428 -0.1607 17.9234
JeKo-1 GDSC2; CTRP2 9.5171 18.8953 2.2315 9.5055
KMS-18 CTRP2 9.7461 24.2601 -0.1932 17.3619
JJN-3 GDSC2; CTRP2 9.8808 21.3914 1.2846 12.1138
EJM GDSC2; CTRP2 10.2793 21.1422 1.6657 10.4185
NB4 GDSC2; CTRP2 10.9902 29.2469 -1.7383 18.785
Karpas-620 GDSC2; CTRP2 11.3432 25.2418 0.4209 12.8694
PL21 CTRP2 11.504 31.1413 -2.2968 20.0788
RPMI-6666 GDSC2; CTRP2 12.0302 27.1045 -0.0128 13.2616
KMS-20 CTRP2 12.446 40.9921 -6.4242 26.0391
HPB-ALL CTRP2 13.1818 29.3352 -0.3265 13.3805
⏷ Show the Full List of 196 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 27 Cell Line(s) in Oesophagus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TE8 CTRP2 8.371 10.3742 5.3776 0.4557
TE15 CTRP2 8.5047 13.5742 4.0787 4.5396
EC-GI-10 GDSC2 0.7822 7.9705 -3.3536 17.8589
TE-8 GDSC2 1.0171 3.5986 -1.0387 4.1392
COLO 680N GDSC2 1.2345 3.2639 -0.7542 2.1622
T.T GDSC2 1.2964 5.8907 -1.9474 8.9361
TE-5 GDSC2 1.5329 3.9798 -0.9043 2.5152
TE-11 GDSC2 1.7663 3.6304 -0.6394 1.0006
TE-9 GDSC2 1.9424 11.8478 -4.3934 19.5391
TE-10 GDSC2 1.9746 4.2563 -0.7946 1.4504
KYSE-140 GDSC2 2.0424 5.0651 -1.1012 2.8171
KYSE-180 GDSC2 2.0928 4.2225 -0.7262 1.0623
KYSE-270 GDSC2 2.2231 4.7764 -0.8882 1.6053
OE21 GDSC2 2.3865 12.5035 -4.3917 18.5312
TE-6 GDSC2; CTRP2 3.9331 6.0571 3.7368 13.8321
KYSE-410 GDSC2; CTRP2 4.7564 7.5886 4.0452 10.5688
KYSE-510 GDSC2; CTRP2 7.389 11.1555 4.5038 4.0253
TE-4 GDSC2; CTRP2 7.6911 9.9367 5.2387 1.162
KYSE-150 GDSC2; CTRP2 7.9475 9.2213 5.6318 0.1334
OE19 GDSC2; CTRP2 7.9797 9.2404 5.6369 0.1208
OE33 GDSC2; CTRP2 8.0479 10.1408 5.3277 0.6851
KYSE-30 CTRP2 8.1441 9.4899 5.61 0.1303
TE-14 CTRP2 8.2305 10.7383 5.1722 1.0447
TE-1 GDSC2; CTRP2 8.3448 10.0749 5.4777 0.258
KYSE-450 GDSC2; CTRP2 8.4078 9.8104 5.5941 0.0972
KYSE-70 GDSC2; CTRP2 8.4406 9.9672 5.5518 0.1358
KYSE-520 GDSC2; CTRP2 8.8925 10.7595 5.4407 0.1827
⏷ Show the Full List of 27 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Pancreas Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
N2a-PK1 CTRP2 8.4081 9.8078 5.5951 0.1026
QGP-1 GDSC2 1.6812 3.9195 -0.7995 1.7954
HPAF-II GDSC2 3.0385 4.3271 2.5672 4.2539
MIA PaCa-2 GDSC2 3.2735 4.1808 2.8516 2.3413
KP-4 GDSC2 3.3083 4.4854 2.7288 2.8464
PL4 GDSC2 3.3837 4.6579 2.7047 2.7993
BxPC-3 GDSC2 3.6176 5.974 2.2336 4.5583
SUIT-2 GDSC2 3.7847 5.3823 2.6472 2.3244
SU.86.86 GDSC2; CTRP2 3.9032 5.0471 3.8864 13.4274
KP-1N GDSC2 4.1999 6.7155 2.2893 3.2869
CFPAC-1 GDSC2 4.3476 6.6889 2.3971 2.5943
KP-3 GDSC2 6.0521 8.1972 2.6159 0.4353
Panc 04.03 GDSC2; CTRP2 6.2664 9.3931 4.5513 5.4947
MZ-PC-1 GDSC2 6.5577 8.6929 2.6311 0.2572
PSN1 GDSC2; CTRP2 6.8315 10.882 4.2461 5.7823
Panc 03.27 GDSC2; CTRP2 7.0262 9.9811 4.8219 3.3039
PaTu 8988t GDSC2; CTRP2 7.5079 8.5414 5.708 0.128
Panc 05.04 CTRP2 7.9441 9.4418 5.5512 0.2715
KP-2 GDSC2; CTRP2 7.9918 9.7064 5.472 0.3862
PaTu 8902 GDSC2; CTRP2 8.0056 9.3732 5.5998 0.163
SNU-410 CTRP2 8.0626 11.2064 4.8879 2.0812
YAPC GDSC2; CTRP2 8.0847 9.2295 5.6781 0.0642
HPAC GDSC2; CTRP2 8.1689 9.6036 5.5793 0.1546
PANC-1 CTRP2 8.1876 10.0246 5.4333 0.4134
Hs 766T GDSC2; CTRP2 8.2234 9.915 5.4884 0.2756
DAN-G GDSC2; CTRP2 8.225 9.6539 5.5823 0.1397
L3.3 CTRP2 8.2456 9.3631 5.6885 0.0444
SW1990 GDSC2; CTRP2 8.2467 11.1243 5.0201 1.3959
PK-59 CTRP2 8.267 9.9071 5.5082 0.247
HuP-T4 GDSC2; CTRP2 8.2756 10.0812 5.448 0.329
TCC-Pan2 CTRP2 8.3811 9.6415 5.6419 0.0645
PK-45H CTRP2 8.4645 10.4653 5.3818 0.4111
Panc 08.13 GDSC2; CTRP2 8.5489 10.3136 5.4701 0.2171
Capan-1 GDSC2; CTRP2 8.6524 10.276 5.5215 0.1334
AsPC-1 GDSC2; CTRP2 8.8466 10.6887 5.4486 0.1819
Panc 02.03 GDSC2; CTRP2 8.8593 10.2477 5.6027 0.0456
Capan-2 GDSC2; CTRP2 8.9124 10.6845 5.4739 0.1418
Panc 10.05 GDSC2; CTRP2 9.1438 11.0747 5.4225 0.159
HuP-T3 GDSC2; CTRP2 10.3892 20.6048 1.9881 9.2591
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 72 Cell Line(s) in Skin Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SH4 CTRP2 13.4183 31.2832 -1.0865 15.0245
CP66-MEL GDSC2 0.7611 2.8025 -0.829 3.4046
M14 GDSC2 0.9484 5.8525 -2.1784 11.1004
SH-4 GDSC2 0.9925 3.0576 -0.8021 2.815
CHL-1 GDSC2 1.1694 4.161 -1.2053 4.8222
WM115 GDSC2 1.1892 2.8129 -0.5827 1.3523
LB373-MEL-D GDSC2 1.2308 2.6961 -0.5129 0.9812
CP50-MEL-B GDSC2 1.3065 3.3575 -0.7556 2.0655
SK-MEL-1 GDSC2 1.3654 2.9416 -0.5488 1.0001
451Lu GDSC2 1.4088 7.5356 -2.668 12.7412
VMRC-MELG GDSC2 1.486 3.3184 -0.6455 1.302
MMAc-SF GDSC2 1.4916 3.9152 -0.8987 2.5461
Mel Ho GDSC2 1.5367 3.4025 -0.6554 1.2918
COLO 783 GDSC2 1.6434 4.0342 -0.8682 2.1785
LB2518-MEL GDSC2 1.6817 2.9321 -0.4091 0.2898
MeWo GDSC2 1.7243 5.5457 -1.5015 5.4868
RPMI-7951 GDSC2 1.738 3.8692 -0.75 1.5002
DJM-1 GDSC2 1.7966 4.3482 -0.9224 2.2488
GAK GDSC2 1.8122 3.1292 -0.4298 0.2856
G-mel GDSC2 1.8192 4.2248 -0.8582 1.9094
HMV-II GDSC2 1.8311 4.3906 -0.9225 2.205
UACC-62 GDSC2 1.8326 3.5025 -0.5601 0.655
MZ-MEL-2 GDSC2 1.8909 13.5707 -5.2811 22.8805
WM1552C GDSC2 1.958 3.7128 -0.5873 0.6623
IST-MEL1 GDSC2 1.9718 5.0854 -1.1483 3.1554
COLO 679 GDSC2 1.9913 3.727 -0.5787 0.613
MZ-MEL-7 GDSC2 2.0245 3.5953 -0.5163 0.4107
A-431 GDSC2 2.1602 4.9533 -0.9923 2.1407
Hs 938.T GDSC2 2.1806 10.5385 -3.5811 15.5289
A-388 GDSC2 2.2219 6.0183 -1.4213 4.2164
WM35 GDSC2 2.3195 4.4028 -0.6974 0.7903
WM278 GDSC2 2.6241 15.0983 -5.4896 21.9431
WM266-4 CTRP2 2.6847 4.0347 2.6796 22.3998
RVH-421 GDSC2; CTRP2 3.8368 5.6635 3.7275 14.142
WM983B CTRP2 3.9809 6.2004 3.748 14.5676
HT-144 GDSC2; CTRP2 4.7812 7.6603 4.0384 10.5343
WT2-iPS GDSC2; CTRP2 4.8338 8.8591 3.5341 12.3229
Hs 944.T CTRP2 4.9831 9.43 3.4023 13.3259
IGR-37 GDSC2; CTRP2 5.5168 8.9875 4.1129 8.6232
SK-MEL-24 GDSC2; CTRP2 5.7561 9.6814 3.9804 8.6699
UACC-257 GDSC2; CTRP2 6.8247 12.2545 3.5633 8.4365
SK-MEL-2 GDSC2; CTRP2 6.94 8.0645 5.647 0.5121
SK-MEL-28 GDSC2; CTRP2 7.2078 8.1065 5.7491 0.1445
Hs 839.T CTRP2 7.4369 8.3562 5.7469 0.0982
Hs 895.T CTRP2 7.5962 9.1229 5.5265 0.4713
IGR-39 CTRP2 7.6203 8.9131 5.6167 0.2603
SK-MEL-30 GDSC2; CTRP2 7.7521 9.0752 5.6096 0.2144
K029AX CTRP2 7.7815 9.0351 5.6355 0.1768
Hs 688(A).T CTRP2 7.8162 8.6594 5.7765 0.0251
SK-MEL-3 GDSC2; CTRP2 7.8281 9.3109 5.553 0.2897
Hs 852.T CTRP2 7.8426 9.5503 5.4681 0.4884
HMCB CTRP2 7.8519 8.8458 5.7267 0.0549
G-361 GDSC2; CTRP2 7.9257 9.7959 5.409 0.5533
A2058 GDSC2; CTRP2 7.9315 9.092 5.6709 0.0914
SK-MEL-5 GDSC2; CTRP2 7.933 9.1273 5.6593 0.1036
Hs 936.T CTRP2 7.9378 9.0924 5.6731 0.0941
WM1799 CTRP2 7.9607 9.3443 5.5931 0.1954
A101D GDSC2; CTRP2 8.0038 9.2679 5.6362 0.1173
SK-MEL-31 GDSC2; CTRP2 8.0289 15.7325 2.7381 9.7184
WM793 GDSC2; CTRP2 8.0336 9.3255 5.627 0.1226
Mel JuSo GDSC2; CTRP2 8.1322 9.518 5.5958 0.1413
IPC-298 GDSC2; CTRP2 8.1792 9.3564 5.6681 0.0617
COLO 829 GDSC2; CTRP2 8.1859 9.8174 5.5093 0.2522
A-375 GDSC2; CTRP2 8.1889 9.7023 5.5518 0.1871
LOX-IMVI GDSC2; CTRP2 8.2498 9.9535 5.4847 0.2739
MDA-MB-435S CTRP2 8.2994 9.2799 5.7337 0.0189
COLO 800 GDSC2; CTRP2 8.3633 9.8962 5.5484 0.1542
Hs 940.T GDSC2; CTRP2 8.4367 11.1103 5.1186 0.996
Hs 294T CTRP2 9.3656 14.8912 3.9862 3.9528
COLO 792 GDSC2; CTRP2 10.0477 23.1748 0.5423 14.1331
IGR-1 GDSC2; CTRP2 11.7684 26.0169 0.3303 12.6281
EquiPSC Line K2 GDSC2 1.7191 10.1141 -3.7057 17.1527
⏷ Show the Full List of 72 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 11 Cell Line(s) in Aero Dig Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
OACP4 C GDSC2 1.1598 5.4712 -1.8396 8.6089
ESO-26 GDSC2 1.5004 3.5544 -0.7374 1.717
KYAE-1 GDSC2 1.5178 7.6415 -2.6416 12.3441
KYSE-50 GDSC2 1.7778 5.1203 -1.2741 4.1244
KYSE-220 GDSC2 1.8345 4.0871 -0.7928 1.5891
HCE-4 GDSC2 1.9161 4.1838 -0.793 1.5032
ESO-51 GDSC2 2.0186 3.9765 -0.6627 0.883
SK-GT-4 GDSC2 2.1908 8.1699 -2.4352 9.7793
FLO-1 GDSC2 2.889 13.8685 -4.699 18.6393
OACM5.1 C GDSC2 2.9417 5.0832 -0.6991 0.4668
TE-12 GDSC2 3.3082 7.2494 -1.3798 2.6316
⏷ Show the Full List of 11 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Ascites Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
COLO 684 GDSC2 1.8258 6.2665 -1.7737 6.8399
Cancer Drug Sensitivity Data Curated from 34 Cell Line(s) in Autonomic Ganglia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SJNB-12 GDSC2 -7.6224 -2.7525 -7.7602 70.56
CHP-126 GDSC2; CTRP2 -5.3621 2.399 -5.6313 66.8027
SJNB-17 GDSC2 -4.7536 3.2578 -6.3351 48.6367
KP-N-RT-BM-1 GDSC2 -3.1968 4.6137 -5.3132 39.3034
NH-12 GDSC2 -0.6862 9.6688 -5.4175 30.1688
SJNB-14 GDSC2 -0.3542 2.8728 -1.7413 12.0789
TGW GDSC2 -0.246 5.4799 -2.9476 18.7699
LA-N-6 GDSC2 0.0148 4.3934 -2.1844 13.6542
NB(TU)1 GDSC2 0.0197 8.7617 -4.3644 24.4548
KP-N-YS GDSC2 0.3573 3.6891 -1.5559 8.8433
SK-N-MC-IXC GDSC2 0.7077 3.1682 -1.0401 4.7894
SK-N-BE(2)-M17 GDSC2 0.7853 3.878 -1.33 6.3866
MHH-NB-11 GDSC2 0.7895 7.204 -2.9671 15.8854
SiMa GDSC2 0.986 10.2868 -4.3466 21.7025
SK-N-DZ GDSC2 1.0028 4.6423 -1.5479 7.2183
SK-N-AS GDSC2 1.0513 5.875 -2.1141 10.476
CHP-212 GDSC2 1.1335 4.7357 -1.5028 6.6617
SJNB-5 GDSC2 1.1652 7.5172 -2.8372 14.2365
SJNB-6 GDSC2 1.2244 15.0199 -6.5156 28.029
IMR-5 GDSC2 1.2927 12.1624 -5.0403 23.4923
GOTO GDSC2 1.4032 5.1559 -1.5233 6.2248
SJNB-13 GDSC2 1.5664 3.5644 -0.7081 1.4995
SJNB-10 GDSC2 1.641 4.9323 -1.2699 4.3298
NB69 GDSC2 1.9221 14.7981 -5.8646 24.6379
SJNB-7 GDSC2 2.0638 10.3129 -3.5541 15.6655
CHP-134 GDSC2 2.2459 3.6924 -0.4671 0.2144
GI-ME-N GDSC2 2.6232 7.2311 -1.7342 5.246
SK-N-BE(2) CTRP2 3.5555 9.781 1.842 22.9134
KP-N-YN GDSC2; CTRP2 6.1625 11.4612 3.4338 10.0577
KP-N-SI9s CTRP2 8.1258 9.3219 5.6611 0.0784
SK-N-FI GDSC2; CTRP2 8.2354 9.751 5.552 0.1762
SK-N-SH GDSC2; CTRP2 9.6455 25.8826 -1.0571 18.9653
Kelly GDSC2; CTRP2 10.6169 24.8616 0.1197 14.5975
NB1 GDSC2; CTRP2 11.8706 24.8598 0.9352 10.8044
⏷ Show the Full List of 34 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Biliary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuCC-T1 GDSC2 1.2925 3.3152 -0.7447 2.0289
SNU-869 CTRP2 7.699 12.6942 3.9768 5.9581
Cancer Drug Sensitivity Data Curated from 85 Cell Line(s) in Breast Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HCC1500 GDSC2; CTRP2 -5.0648 0.8074 -5.1472 67.0587
COLO 824 GDSC2 -3.1276 4.8968 -5.373 39.0248
DU4475 GDSC2 0.0442 10.1926 -5.0595 26.8224
MDA-MB-330 GDSC2 0.421 3.4843 -1.4049 7.7356
HCC2157 GDSC2 0.7602 7.3271 -3.0509 16.3989
BT-474 GDSC2 1.2079 5.8156 -1.973 9.2542
HCC70 GDSC2 1.2585 4.6887 -1.3968 5.7525
HCC1599 GDSC2 1.3335 3.2361 -0.6884 1.6821
CAL-148 GDSC2 1.3408 2.7743 -0.4927 0.7864
Evsa-T GDSC2 1.3795 5.4916 -1.6986 7.2749
Hs 578T GDSC2 1.4442 4.3531 -1.1232 3.8321
OCUB-M GDSC2 1.4849 6.9473 -2.3274 10.6559
MFM-223 GDSC2 1.5293 3.1085 -0.5398 0.8087
EFM-192A GDSC2 1.5303 4.3033 -1.0498 3.2849
MDA-MB-436 GDSC2 1.5456 3.3513 -0.63 1.1663
CAMA-1 GDSC2 1.5535 5.8951 -1.7751 7.3605
CAL-120 GDSC2 1.5675 7.2477 -2.4152 10.9588
UACC-893 GDSC2 1.5749 11.2169 -4.3561 20.2138
MDA-MB-175-VII GDSC2 1.6219 4.39 -1.0361 3.0691
BT-20 GDSC2 1.6443 5.5797 -1.5675 5.9903
MCF-7 GDSC2 1.6468 7.2026 -2.3384 10.3588
HCC1806 GDSC2 1.6601 3.4931 -0.6334 1.069
JIMT-1 GDSC2 1.7792 3.4338 -0.5566 0.6777
HCC1937 GDSC2 1.8341 5.91 -1.6023 5.8561
HCC1569 GDSC2 1.8705 9.3111 -3.2038 14.3934
HCC1187 GDSC2 1.9074 10.1179 -3.5709 16.0555
EFM-19 GDSC2 1.981 4.6005 -0.9345 2.0716
HCC1954 GDSC2 2.026 9.1287 -3.0061 13.0648
YMB-1-E GDSC2 2.0626 10.2806 -3.5393 15.5995
HDQ-P1 GDSC2 2.0725 4.1143 -0.6928 0.9488
HCC2218 GDSC2 2.2481 4.1473 -0.6307 0.6189
MRK-nu-1 GDSC2 2.2508 3.7554 -0.4873 0.2512
BT-483 GDSC2 2.2775 6.6107 -1.6555 5.3631
UACC-812 GDSC2 2.5224 4.3823 -0.608 0.4209
HCC1395 GDSC2 2.9674 10.3836 -2.9761 11.003
MDA-MB-453 GDSC2; CTRP2 5.4518 8.3316 4.3759 7.7158
CAL-85-1 GDSC2; CTRP2 5.5178 7.2614 4.956 5.3365
Hs 578Bst CTRP2 5.6733 7.127 5.1695 4.4625
MDA-MB-415 GDSC2; CTRP2 5.7318 11.7872 2.9085 12.8509
HCC1419 GDSC2; CTRP2 7.5673 13.5889 3.4537 7.7165
MDA-MB-231 GDSC2; CTRP2 7.6223 10.4853 4.9603 2.1177
ZR-75-1 CTRP2 7.8492 8.9551 5.6886 0.0917
SK-BR-3 CTRP2 7.9838 10.2116 5.2694 0.9303
ZR-75-30 GDSC2; CTRP2 8.0472 9.9885 5.3873 0.5431
HCC38 GDSC2; CTRP2 8.0945 9.8709 5.4526 0.3841
MDA-MB-361 GDSC2; CTRP2 8.1624 9.7421 5.5274 0.2295
MDA-MB-468 GDSC2; CTRP2 8.1866 13.0559 4.1225 4.4485
AU565 GDSC2; CTRP2 8.2167 12.9777 4.1775 4.2184
BT-549 GDSC2; CTRP2 8.2285 10.2844 5.3516 0.5393
MDA-MB-157 GDSC2; CTRP2 8.2989 10.182 5.42 0.3716
CAL-51 GDSC2; CTRP2 8.4811 10.4455 5.3959 0.3536
T-47D GDSC2; CTRP2 9.0205 15.5407 3.4878 5.749
HCC202 CTRP2 9.2279 11.646 5.2515 0.3955
HCC1143 GDSC2; CTRP2 9.2846 11.3698 5.3711 0.1915
HCC1428 GDSC2; CTRP2 10.8454 22.4925 1.3943 10.5757
BT 239 CTRP2 1.0511 8.2103 -0.1189 36.5306
BT 416 CTRP2 2.1387 2.9757 2.1387 26.0201
BT 286 CTRP2 3.5737 8.8704 2.2696 21.2965
BT 428 CTRP2 4.6535 12.4091 1.6396 20.8956
BT 131 CTRP2 6.3291 11.2967 3.6516 9.5043
BT 139 CTRP2 7.1202 12.1884 3.8163 7.468
BT 340 CTRP2 7.1271 9.2773 5.2163 1.863
BT 320 CTRP2 7.3249 8.532 5.6375 0.3395
BT 422 CTRP2 7.3483 9.4188 5.2799 1.4043
BT 232 CTRP2 7.4438 9.3221 5.3725 1.0125
BT 216 CTRP2 7.4536 10.0989 5.0363 2.1671
BT 333 CTRP2 7.5224 8.9958 5.5436 0.4677
BT 444 CTRP2 7.6647 9.0671 5.5773 0.3233
BT 498 CTRP2 7.6791 8.8728 5.6546 0.1743
BT 440 CTRP2 7.764 9.6203 5.4054 0.691
BT 187 CTRP2 7.8251 10.9208 4.8816 2.3358
BT 159 CTRP2 7.8361 14.6156 3.1446 9.0461
BT 328 CTRP2 7.8641 9.4677 5.509 0.386
BT 179 CTRP2 7.8719 12.0057 4.4142 4.0223
BT 224 CTRP2 7.8977 9.2827 5.5911 0.2163
BT 172 CTRP2 7.9135 9.4879 5.5218 0.3392
BT 504 CTRP2 7.955 9.1099 5.6732 0.0912
BT 330 CTRP2 7.9821 9.3366 5.6039 0.1735
BT 228 CTRP2 8.2065 14.0535 3.6667 6.4826
BT147 CTRP2 8.2391 14.5269 3.4633 7.2259
BT 245 CTRP2 8.3392 17.1359 2.2752 11.5727
BT 271 CTRP2 8.4518 18.5098 1.6863 13.4906
BT 359 CTRP2 8.4684 9.9776 5.5583 0.1323
BT 482 CTRP2 9.5498 20.2192 1.6226 12.1035
BT 231 CTRP2 9.6443 18.9887 2.2703 9.7584
⏷ Show the Full List of 85 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 62 Cell Line(s) in Central Nervous System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
AM-38 GDSC2; CTRP2 0.0204 24.3568 -8.5143 45.7242
LN-18 GDSC2 0.6505 4.6062 -1.786 9.5021
PFSK-1 GDSC2 0.7147 12.0831 -5.4568 26.3225
D283 Med GDSC2 0.7761 2.6319 -0.7391 2.8458
SF295 GDSC2 0.7994 2.38 -0.6082 2.0541
GI-1 GDSC2 0.8359 3.1511 -0.9452 3.9457
M059J GDSC2 0.9009 3.0853 -0.8721 3.3856
H4 GDSC2 0.9167 6.578 -2.5598 13.3538
SF126 GDSC2 1.0491 2.8095 -0.6568 1.9214
LN-405 GDSC2 1.074 3.4225 -0.9205 3.3458
D-423MG GDSC2 1.3339 4.0544 -1.0528 3.6394
D-542MG GDSC2 1.3369 4.3683 -1.1959 4.4496
MOG-G-CCM GDSC2 1.3771 8.834 -3.3285 16.2095
Hs 683 GDSC2 1.4107 3.3757 -0.7078 1.6846
NMC-G1 GDSC2 1.4684 3.0599 -0.5483 0.8993
Onda 10 GDSC2 1.5624 3.6243 -0.7352 1.6315
D-263MG GDSC2 1.6066 3.5617 -0.6871 1.359
D-392MG GDSC2 1.6098 5.4171 -1.5134 5.7662
Daoy GDSC2 1.6103 4.1984 -0.9577 2.6824
LN-229 GDSC2 1.6294 10.1424 -3.7856 17.7248
D-566MG GDSC2 1.75 3.1905 -0.4768 0.4409
CAS-1 GDSC2 1.7861 3.3105 -0.5068 0.5113
D-336MG GDSC2 1.8572 4.08 -0.7788 1.5021
D-247MG GDSC2 1.8787 3.8244 -0.6654 1.0059
MOG-G-UVW GDSC2 1.9159 5.6664 -1.4405 4.8102
GB-1 GDSC2 1.9363 6.1711 -1.66 5.9946
ONS-76 GDSC2 1.9771 4.9347 -1.0796 2.7965
KNS-81-FD GDSC2 2.0824 10.8684 -3.8116 16.7852
SK-MG-1 GDSC2 2.1477 4.3338 -0.7455 1.0912
KINGS-1 GDSC2 2.2247 4.5652 -0.8024 1.2483
SF539 GDSC2; CTRP2 2.3531 3.0479 2.3531 23.057
D-502MG GDSC2 2.3886 6.9783 -1.7567 5.7423
D-245MG GDSC2 2.4252 5.7545 -1.1959 2.7905
Onda 11 GDSC2 2.4259 4.5052 -0.6917 0.7048
KS-1 [Human Krukenberg tumour] GDSC2 2.6034 5.4036 -0.9634 1.5586
U-87MG ATCC GDSC2 3.2145 13.6549 -4.3698 16.7121
SF268 GDSC2; CTRP2 3.3347 5.1983 3.2678 17.1387
KNS-60 CTRP2 3.7939 4.8442 3.7854 15.0215
U-251MG GDSC2; CTRP2 5.1696 6.5892 4.9006 6.3914
KALS-1 GDSC2; CTRP2 6.156 8.2753 5.0205 3.8377
SW1783 GDSC2; CTRP2 6.7084 19.6011 -0.1888 21.3117
GaMG GDSC2; CTRP2 7.3923 10.0709 5.0127 2.1771
CCF-STTG1 CTRP2 7.5798 8.8279 5.632 0.2454
KNS-81 CTRP2 7.6492 8.6248 5.7307 0.0786
M059K CTRP2 7.7265 9.289 5.5189 0.4252
U-118MG GDSC2; CTRP2 7.8104 10.051 5.2511 1.0378
YKG-1 GDSC2; CTRP2 7.8166 9.3254 5.5429 0.3131
TM-31 CTRP2 7.8473 9.2078 5.5986 0.2185
KNS-42 GDSC2; CTRP2 7.8695 12.7263 4.0746 5.0104
KG-1-C CTRP2 7.9375 9.0902 5.6737 0.0934
GOS-3 CTRP2 7.9526 9.8093 5.4156 0.5598
GMS-10 CTRP2 8.0816 9.1294 5.7105 0.0441
DK-MG GDSC2; CTRP2 8.1433 9.6286 5.5608 0.1852
42-MG-BA GDSC2; CTRP2 8.1838 9.7287 5.5405 0.2046
SW1088 GDSC2; CTRP2 8.2683 15.2907 3.1176 8.0102
YH-13 GDSC2; CTRP2 8.3113 9.6502 5.6147 0.0911
8-MG-BA GDSC2; CTRP2 8.3731 9.6045 5.6515 0.0545
Becker GDSC2; CTRP2 8.6308 10.7783 5.3329 0.4183
SNB-75 GDSC2; CTRP2 8.6678 10.5838 5.4187 0.2625
DBTRG-05MG GDSC2; CTRP2 8.6925 10.7044 5.3847 0.3088
A-172 GDSC2; CTRP2 11.733 23.6178 1.4244 9.5169
T98G GDSC2; CTRP2 13.6456 27.1953 0.9308 9.0261
⏷ Show the Full List of 62 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 3 Cell Line(s) in Digestive System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TGBC1TKB GDSC2 1.0587 6.5637 -2.4467 12.3652
TGBC24TKB GDSC2 1.3047 6.9317 -2.4478 11.7783
ETK-1 GDSC2 2.172 4.865 -0.9495 1.9301
Cancer Drug Sensitivity Data Curated from 13 Cell Line(s) in Endometrium Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MFE-280 GDSC2 1.3843 4.7069 -1.3241 5.1015
RL95-2 GDSC2 2.2872 7.2256 -1.9313 6.8626
KLE GDSC2 2.9326 12.729 -4.1173 16.2621
HEC-151 CTRP2 4.2884 5.4612 4.25 11.829
EFE-184 CTRP2 4.9768 7.3513 4.3753 9.3912
HEC-1-A CTRP2 5.6935 8.751 4.3886 7.668
MFE-319 GDSC2; CTRP2 7.6908 11.7799 4.4051 4.0169
ESS-1 GDSC2; CTRP2 7.7171 9.4127 5.4665 0.5224
EN GDSC2; CTRP2 7.7411 9.0625 5.6099 0.2173
HEC-50B CTRP2 8.3136 12.743 4.344 3.7713
MFE-296 GDSC2; CTRP2 8.3447 10.0453 5.4884 0.2414
JHUEM-3 CTRP2 8.7395 10.4787 5.4827 0.1723
AN3-CA GDSC2; CTRP2 11.5031 22.0568 2.0002 8.0095
⏷ Show the Full List of 13 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 37 Cell Line(s) in Kidney Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-498 GDSC2 0.7366 4.8214 -1.8277 9.54
RXF 393L GDSC2 0.7555 5.9487 -2.3705 12.698
A-704 GDSC2 1.1439 5.6685 -1.9468 9.2775
KTCTL-26A GDSC2 1.3308 4.537 -1.2785 4.9384
KTCTL-21 GDSC2 1.4313 7.2998 -2.5367 11.9737
LB2241-RCC GDSC2 1.4869 4.8947 -1.347 5.0414
LB996-RCC GDSC2 1.574 5.0738 -1.3759 5.0467
HA7-RCC GDSC2 1.6187 6.7179 -2.1245 9.2516
SW13 GDSC2 1.6737 3.9647 -0.8225 1.9151
BB65-RCC GDSC2 1.6875 5.3706 -1.4432 5.2229
KTCTL-195 GDSC2 1.6979 3.9892 -0.8204 1.8753
769-P GDSC2 1.8534 3.5406 -0.5658 0.6603
OS-RC-2 GDSC2 1.9833 10.9516 -3.9238 17.5007
NCC021 GDSC2 1.9871 4.1562 -0.7481 1.2424
KTCTL-140 GDSC2 1.9894 4.4606 -0.8716 1.7768
TUHR10TKB CTRP2 1.9947 3.5412 1.9903 26.9944
SN12C GDSC2 2.0768 4.0544 -0.6676 0.857
BFTC-909 GDSC2 2.0952 13.9058 -5.2934 22.4565
NCC010 GDSC2 2.1368 5.1047 -1.0684 2.5323
KTCTL-13 GDSC2 2.1974 7.5295 -2.1289 8.1079
KMRC-20 GDSC2 2.381 9.051 -2.7281 10.9361
UO-31 GDSC2; CTRP2 2.5219 3.9889 2.5151 22.0241
LB1047-RCC GDSC2 2.5593 4.9079 -0.7886 0.9363
KTCTL-1M GDSC2 2.6261 4.6274 -0.6565 0.4976
SW156 GDSC2 2.804 4.7003 -0.6148 0.3298
TK-10 GDSC2 2.8041 9.5105 -2.6709 9.8214
VMRC-RCZ GDSC2; CTRP2 5.158 7.2089 4.6231 7.4435
RCC10RGB GDSC2; CTRP2 7.7015 9.3827 5.4714 0.5189
Caki-2 CTRP2 7.7687 10.4135 5.0743 1.7167
KMRC-3 CTRP2 7.7843 16.7525 2.0621 13.2204
KMRC-2 CTRP2 8.0525 9.2777 5.6503 0.1
VMRC-RCW GDSC2; CTRP2 8.2228 10.1211 5.4115 0.417
CAL-54 GDSC2; CTRP2 8.2491 12.9506 4.2099 4.0762
Caki-1 GDSC2; CTRP2 8.2871 10.4447 5.315 0.5951
ACHN GDSC2; CTRP2 8.3163 9.879 5.537 0.1785
KMRC-1 GDSC2; CTRP2 8.5311 15.3514 3.2644 7.1384
786-O GDSC2; CTRP2 8.6167 10.648 5.3754 0.3468
⏷ Show the Full List of 37 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 53 Cell Line(s) in Large Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
LS180 GDSC2 0.6077 3.1049 -1.0797 5.2578
SK-CO-1 GDSC2 0.7508 6.1294 -2.4637 13.2412
HCT 116 GDSC2 0.9229 5.6142 -2.08 10.5869
LS411N GDSC2 0.9888 3.8845 -1.1928 5.1118
SW837 GDSC2 1.1138 3.4193 -0.8947 3.1282
SNU-C1 GDSC2 1.1568 3.0816 -0.717 2.0805
COLO 320HSR GDSC2 1.21 12.1445 -5.0956 23.8868
HT-29 GDSC2 1.2133 6.6121 -2.3575 11.4881
GP5d GDSC2 1.2362 3.4622 -0.8417 2.6294
SNU-175 GDSC2 1.2765 3.664 -0.9092 2.9349
SW626 GDSC2 1.2911 4.1148 -1.1068 4.0218
DiFi GDSC2 1.437 4.3567 -1.1292 3.8913
SNU-81 GDSC2 1.4657 3.4481 -0.7102 1.6281
SW1463 GDSC2 1.5512 3.7891 -0.8114 2.0161
SW48 GDSC2 1.6316 12.9423 -5.1667 23.1029
HT115 GDSC2 1.7353 3.2528 -0.5062 0.5402
HCC2998 GDSC2 1.8221 4.5581 -0.9995 2.6007
COLO205 GDSC2 1.8814 7.6603 -2.3984 10.2174
SNU-283 GDSC2 2.2234 4.2153 -0.6666 0.7511
CaR-1 GDSC2 2.2833 4.5912 -0.7861 1.1354
SNU-C2B GDSC2 2.3442 7.0788 -1.8291 6.2078
NCI-H747 GDSC2; CTRP2 3.5322 8.6969 2.3032 19.9794
C2BBe1 GDSC2; CTRP2 6.6198 8.7172 5.1518 2.6028
COLO 320 CTRP2 7.2386 12.5223 3.7387 7.5967
SNU-503 CTRP2 7.3866 13.0994 3.5633 8.074
HCT 8 CTRP2 7.5963 8.6479 5.7034 0.1222
SNU-C4 CTRP2 7.683 8.7754 5.6906 0.1205
HCC-56 CTRP2 7.6865 8.6679 5.7292 0.0744
SW948 GDSC2; CTRP2 7.713 9.3339 5.4956 0.4566
RCM-1 [Human ESC] GDSC2; CTRP2 7.9234 9.2594 5.6092 0.169
SW1116 GDSC2; CTRP2 7.9268 9.9438 5.3508 0.6941
LS123 GDSC2; CTRP2 7.9659 9.4085 5.5719 0.214
NCI-H508 GDSC2; CTRP2 8.0348 9.3938 5.6034 0.1517
LS1034 GDSC2; CTRP2 8.0408 9.3278 5.6288 0.1191
MDST8 GDSC2; CTRP2 8.0723 13.6047 3.7913 5.7982
HT-55 GDSC2; CTRP2 8.0944 9.2323 5.6805 0.0612
HCT 15 GDSC2; CTRP2 8.1195 9.5302 5.5868 0.1553
RKO GDSC2; CTRP2 8.2115 9.9244 5.4802 0.2932
KM12 GDSC2; CTRP2 8.2165 9.5792 5.6052 0.115
CCK-81 GDSC2; CTRP2 8.2279 10.0907 5.4251 0.3884
COLO201 CTRP2 8.3365 9.5084 5.6711 0.048
COLO 678 GDSC2; CTRP2 8.3693 13.9551 3.818 5.3393
NCI-H716 GDSC2; CTRP2 8.413 10.3708 5.3961 0.377
LoVo GDSC2; CTRP2 8.4295 10.2478 5.448 0.2817
SNU-1033 CTRP2 8.5314 10.583 5.3652 0.4192
CW-2 GDSC2; CTRP2 8.5701 10.3553 5.4633 0.2218
SW1417 GDSC2; CTRP2 8.5897 11.4642 5.0473 1.0915
T84 GDSC2; CTRP2 8.6374 10.8334 5.315 0.4497
SW620 GDSC2; CTRP2 8.6402 10.2378 5.5302 0.1261
CL-11 GDSC2; CTRP2 8.8466 10.6049 5.4777 0.1485
SNU-407 GDSC2; CTRP2 8.847 10.6667 5.4564 0.1725
SNU-C5 GDSC2; CTRP2 9.0478 16.8319 2.9012 7.7866
SNU-61 GDSC2; CTRP2 10.5324 22.7623 1.0647 11.9703
⏷ Show the Full List of 53 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Leukemia Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
MO-T GDSC2 0.7669 4.8312 -1.8101 9.3584
Cancer Drug Sensitivity Data Curated from 22 Cell Line(s) in Liver Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
SNU-886 CTRP2 1.2801 26.7102 -8.4854 44.3027
Huh-7 GDSC2 1.3417 7.7855 -2.8391 13.8143
Hep-G2/C3A GDSC2 1.456 3.3942 -0.6923 1.5544
JHH-7 GDSC2 2.0019 5.3538 -1.2501 3.6435
Hep 3B2.1-7 GDSC2 2.332 14.9288 -5.6213 22.9894
HLE GDSC2 2.4306 4.3676 -0.6386 0.5443
JHH-2 GDSC2; CTRP2 3.6915 9.5041 2.1047 20.2904
SNU-761 CTRP2 4.307 5.8875 4.1887 11.9852
PLC/PRF/5 CTRP2 5.9492 10.5917 3.691 10.0654
JHH-6 GDSC2; CTRP2 7.4372 8.1614 5.8136 0.0299
SNU-398 GDSC2; CTRP2 7.4783 19.9604 0.2423 18.7901
SK-HEP-1 GDSC2; CTRP2 7.6959 9.0719 5.5883 0.2704
Hep-G2 CTRP2 7.8768 9.2195 5.6058 0.1981
SNU-475 CTRP2 7.8988 9.2641 5.5982 0.2042
HuH-6 CTRP2 7.9081 9.8759 5.3694 0.7017
JHH-4 GDSC2; CTRP2 8.1695 11.1807 4.9563 1.6466
HuH-1 GDSC2; CTRP2 8.1738 9.4391 5.6381 0.0881
HLF CTRP2 8.2329 11.7317 4.751 2.3924
SNU-423 GDSC2; CTRP2 8.4023 16.4895 2.6323 9.5757
SNU-449 GDSC2; CTRP2 8.7154 14.9326 3.5801 5.7848
SNU-387 GDSC2; CTRP2 11.1342 22.8071 1.4297 10.156
JHH-1 GDSC2; CTRP2 11.3834 19.9507 2.875 5.4166
⏷ Show the Full List of 22 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 201 Cell Line(s) in Lung Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H889 CTRP2 -7.1304 -5.2793 -7.1304 87.1704
NCI-H1963 GDSC2 -4.609 2.4635 -5.866 47.5681
NCI-H209 GDSC2 -3.084 2.7661 -4.3816 36.3012
DMS 53 GDSC2; CTRP2 -2.4965 3.0335 -2.6601 53.0801
IST-SL2 GDSC2 -2.0709 6.7562 -5.2283 34.3718
NCI-H510A GDSC2; CTRP2 -1.3197 3.9749 -1.5365 46.2802
NCI-H1105 GDSC2; CTRP2 -1.3093 3.4126 -1.4453 46.128
NCI-H526 GDSC2 -1.2268 7.4046 -4.7685 29.9112
NCI-H2141 GDSC2; CTRP2 -0.4928 19.1851 -10.0062 38.0124
NCI-H146 GDSC2 -0.2095 6.4344 -3.3934 20.9207
COR-L303 GDSC2 -0.2056 12.5884 -6.4663 31.5207
NCI-H2196 GDSC2 -0.2001 6.4487 -3.3926 20.8872
COR-L311 GDSC2 0.085 9.4619 -4.6603 25.3778
NCI-H748 GDSC2 0.1118 4.2356 -2.0254 12.4148
NCI-H211 GDSC2 0.1774 5.9143 -2.8107 16.7533
COR-L32 GDSC2 0.1992 5.1976 -2.4347 14.5852
NCI-H345 GDSC2 0.2416 4.5099 -2.0569 12.2357
NCI-H1048 GDSC2 0.301 7.6585 -3.5814 20.2845
BEN GDSC2 0.3918 4.2667 -1.8163 10.36
NCI-H2227 GDSC2 0.5003 8.7039 -3.9423 21.3384
NCI-H2171 GDSC2 0.5103 4.9204 -2.0489 11.4542
NCI-H2135 GDSC2 0.542 2.4728 -0.819 3.8056
NCI-H720 GDSC2 0.6667 6.7031 -2.8134 15.3974
SHP-77 GDSC2 0.6829 5.4311 -2.1696 11.7183
NCI-H2029 GDSC2 0.7269 3.2011 -1.0427 4.7628
NCI-H847 GDSC2 0.7863 3.2908 -1.0452 4.6495
NCI-H1092 GDSC2 0.819 10.1863 -4.4278 22.4616
NCI-H2066 GDSC2 0.8452 3.4372 -1.0754 4.7072
NCI-H69 GDSC2 0.8952 6.8496 -2.7104 14.2377
NCI-H290 GDSC2 0.9035 3.5577 -1.094 4.6966
Ms-1 GDSC2 0.9256 4.0473 -1.3139 5.9753
LB647-SCLC GDSC2 0.9786 3.0767 -0.8195 2.9385
NCI-H1299 GDSC2 0.9984 8.6387 -3.5182 18.0762
NCI-H2347 GDSC2 1.0015 5.1755 -1.808 8.7844
NCI-H1876 GDSC2 1.012 4.3168 -1.3843 6.2127
COR-L279 GDSC2 1.0172 3.7481 -1.1092 4.5559
HCC78 GDSC2 1.0327 3.3692 -0.9215 3.4263
NCI-H835 GDSC2 1.0438 3.7477 -1.0918 4.4
SBC-5 GDSC2 1.0576 10.5846 -4.4388 21.88
COR-L88 GDSC2 1.0722 6.6263 -2.4676 12.4491
SBC-1 GDSC2 1.1284 3.8903 -1.1044 4.31
COR-L23 GDSC2 1.129 5.2754 -1.7663 8.2436
COR-L321 GDSC2 1.1403 2.8653 -0.6311 1.6567
NCI-H2795 GDSC2 1.1567 5.777 -1.9905 9.5047
NCI-H1836 GDSC2 1.167 4.2818 -1.2639 5.1719
UMC-11 GDSC2 1.1727 7.0269 -2.5905 12.8854
NCI-H1975 GDSC2 1.1869 10.9835 -4.5367 21.9273
NCI-H647 GDSC2 1.2136 3.2395 -0.7551 2.198
NCI-H250 GDSC2 1.2277 4.6408 -1.3943 5.8198
VMRC-LCD GDSC2 1.246 5.37 -1.7309 7.7747
Lu-165 GDSC2 1.2559 3.5185 -0.8556 2.6739
NCI-H1581 GDSC2 1.3181 4.017 -1.0452 3.6239
NCI-H3122 GDSC2 1.3194 4.0132 -1.0427 3.6077
LK-2 GDSC2 1.3424 6.8163 -2.3645 11.224
NCI-H3255 GDSC2 1.3438 4.0723 -1.0551 3.6351
NCI-H1155 GDSC2 1.39 8.1127 -2.9643 14.3519
NCI-H1693 GDSC2 1.4338 7.8493 -2.8033 13.405
NCI-H1694 GDSC2 1.4405 3.6458 -0.8085 2.1506
HCC44 GDSC2 1.4707 3.8404 -0.8774 2.4645
NCI-H2810 GDSC2 1.4752 4.85 -1.3336 4.9858
NCI-H322M GDSC2 1.4757 4.9152 -1.3636 5.1577
Lu-99A GDSC2 1.4792 4.2021 -1.0339 3.2915
NCI-H2722 GDSC2 1.5224 6.5693 -2.1188 9.427
NCI-H196 GDSC2 1.5413 5.3647 -1.5324 6.0059
NCI-H1781 GDSC2 1.5789 3.9116 -0.8495 2.1706
CPC-N GDSC2 1.6082 3.5486 -0.6809 1.3296
NCI-H2803 GDSC2 1.6183 3.971 -0.8542 2.1418
NCI-H2869 GDSC2 1.6184 4.2875 -0.9926 2.8539
Calu-3 GDSC2 1.633 8.8012 -3.125 14.591
ABC-1 GDSC2 1.6792 8.0869 -2.7439 12.5209
NCI-H1435 GDSC2 1.6964 3.9775 -0.8163 1.8572
NCI-H1688 GDSC2 1.7447 6.2045 -1.7966 7.1267
NCI-H1838 GDSC2 1.7452 4.1971 -0.8845 2.1278
NCI-H2373 GDSC2 1.749 3.9631 -0.7836 1.6417
NCI-H810 GDSC2 1.7531 9.3332 -3.2985 15.1659
DMS 79 GDSC2 1.7733 3.9167 -0.7523 1.4729
NCI-H596 GDSC2 1.7793 3.417 -0.5501 0.6574
NCI-H2804 GDSC2 1.78 11.9507 -4.5645 20.5846
NCI-H2461 GDSC2 1.7802 6.3541 -1.8442 7.328
NCI-H292 GDSC2 1.7855 3.7232 -0.6676 1.0974
NCI-H513 GDSC2 1.8041 4.7153 -1.0781 3.0314
LCLC-103H GDSC2 1.8127 3.149 -0.4368 0.3022
HCC827 GDSC2 1.8332 3.6211 -0.6057 0.816
NCI-H2009 GDSC2 1.8614 4.7114 -1.045 2.7786
NCI-H1703 GDSC2 1.8696 5.0475 -1.1886 3.517
NCI-H650 GDSC2 1.8704 14.3587 -5.6864 24.2186
NCI-H1437 GDSC2 1.8862 7.655 -2.3926 10.1758
NCI-H727 GDSC2 1.9161 6.0241 -1.6045 5.7205
IST-SL1 GDSC2 1.9165 3.8243 -0.6483 0.9092
NCI-H2591 GDSC2 1.9263 7.1031 -2.1031 8.4946
NCI-H740 GDSC2 1.9409 5.3106 -1.2653 3.8173
NCI-H2291 GDSC2 1.955 4.5551 -0.9285 2.0816
NCI-H1568 GDSC2 1.9844 7.8981 -2.4428 10.2427
NCI-H358 GDSC2 2.0243 8.7347 -2.8171 12.1405
Lu-134-A GDSC2 2.0422 7.4391 -2.1864 8.7247
NCI-H1734 GDSC2 2.0665 4.0749 -0.68 0.9096
NCI-H2595 GDSC2 2.0841 4.1804 -0.7135 1.0209
NCI-H2818 GDSC2 2.0847 4.7114 -0.9289 1.9328
NCI-H82 GDSC2 2.1393 4.149 -0.6771 0.845
NCI-H1770 GDSC2 2.1601 12.4348 -4.5219 19.544
NCI-H2405 GDSC2 2.1633 4.4328 -0.7777 1.2037
LC-2/ad GDSC2 2.1684 4.1526 -0.666 0.7861
NCI-H2369 GDSC2 2.1821 12.1468 -4.3648 18.8786
NCI-H1993 GDSC2 2.1886 4.2956 -0.7124 0.935
NCI-H2731 GDSC2 2.1939 4.8177 -0.9192 1.7703
Lu-135 GDSC2 2.208 4.5822 -0.8168 1.3211
NCI-H838 GDSC2 2.2375 3.7973 -0.5071 0.2984
NCI-H1436 GDSC2 2.249 4.2199 -0.6575 0.705
HCC33 GDSC2 2.2732 12.109 -4.2804 18.3369
PaCa-3 GDSC2 2.3008 9.7849 -3.1332 13.1413
SBC-3 GDSC2 2.3419 4.2697 -0.638 0.59
LC-1/sq GDSC2 2.3475 5.8555 -1.2803 3.3074
HARA [Human squamous cell lung carcinoma] GDSC2 2.348 4.8335 -0.8529 1.3417
CAL-12T GDSC2 2.4576 12.4529 -4.3161 18.0748
HCC366 GDSC2 2.4933 13.3768 -4.7414 19.637
A-427 GDSC2 2.4944 5.5186 -1.0621 2.0874
HOP-62 GDSC2; CTRP2 2.5437 3.7068 2.5422 21.8711
ChaGo-K-1 GDSC2 2.5817 4.6603 -0.6861 0.6003
DMS 454 CTRP2 2.598 5.5509 2.4056 23.6223
NCI-H2087 GDSC2; CTRP2 2.6028 4.1063 2.5939 21.5249
RERF-LC-KJ GDSC2 2.6109 4.1221 -0.4844 0.1533
EMC-BAC-1 GDSC2 2.6486 5.1538 -0.8448 1.0693
EMC-BAC-2 GDSC2 2.6635 5.756 -1.0778 1.9809
NCI-H2030 GDSC2 2.7193 4.4275 -0.5506 0.2327
NCI-H1341 GDSC2 2.735 15.8791 -5.7916 22.6569
NCI-H23 GDSC2 2.7713 4.7443 -0.6427 0.4025
NCI-H1666 GDSC2; CTRP2 2.8987 5.2761 2.7865 20.0082
NCI-H1648 GDSC2 2.9298 5.1646 -0.7331 0.5571
NCI-H64 GDSC2 3.0861 15.6075 -5.4053 20.7104
NCI-H1944 GDSC2; CTRP2 3.1081 5.4738 2.9758 18.7667
NCI-H1793 GDSC2; CTRP2 3.1853 8.8992 1.8577 22.4255
NCI-H1573 GDSC2; CTRP2 3.36 8.4538 2.2298 20.6773
NCI-H2444 GDSC2; CTRP2 3.3802 4.8058 3.3592 16.7077
RERF-LC-Sq1 GDSC2 3.3804 6.4974 -1.0473 1.2554
COLO 668 GDSC2; CTRP2 3.4291 10.3354 1.4612 23.1538
HCC15 GDSC2 3.4996 18.4158 -6.4793 23.1169
NCI-H2228 GDSC2; CTRP2 4.1854 6.3914 3.9113 12.5263
NCI-H2170 GDSC2; CTRP2 4.4977 6.9861 4.0307 11.2687
HCC2935 CTRP2 4.5372 6.0741 4.3914 10.552
LOU-NH91 GDSC2; CTRP2 4.8491 9.3578 3.3101 13.1444
NCI-H1563 GDSC2; CTRP2 5.3407 10.1319 3.3882 11.8032
T3M-10 CTRP2 5.4625 10.656 3.2373 12.9373
NCI-H2110 GDSC2; CTRP2 5.7384 9.5103 4.0503 8.4295
NCI-H522 GDSC2; CTRP2 5.8227 10.0797 3.8392 9.0969
NCI-H1915 GDSC2; CTRP2 5.8936 12.0042 2.938 12.4601
KNS-62 GDSC2; CTRP2 6.0341 8.9844 4.5658 5.8455
NCI-H841 GDSC2; CTRP2 6.0868 10.5628 3.8205 8.6832
LUDLU-1 CTRP2 6.1226 11.6876 3.2877 11.3935
Sq-1 CTRP2 6.6499 13.924 2.5972 13.1662
NCI-H524 GDSC2; CTRP2 6.8838 18.023 0.7394 18.3158
NCI-H1395 CTRP2 7.3431 15.4108 2.3945 12.7239
A-549 GDSC2; CTRP2 7.432 16.4861 1.93 13.4958
NCI-H2286 CTRP2 7.5612 12.2671 4.0883 5.7078
NCI-H226 GDSC2; CTRP2 7.6303 8.8758 5.6345 0.2095
SW1573 GDSC2; CTRP2 7.6439 16.1368 2.2612 12.0006
EPLC-272H GDSC2; CTRP2 7.6957 9.7662 5.3129 0.9409
NCI-H2085 GDSC2; CTRP2 7.7626 9.7882 5.3365 0.8302
EKVX GDSC2; CTRP2 7.8475 13.894 3.5017 7.1631
NCI-H2081 GDSC2; CTRP2 7.8584 17.7557 1.6232 13.8708
NCI-H661 GDSC2; CTRP2 7.8743 11.7896 4.5158 3.4064
NCI-H2126 CTRP2 7.8936 9.1464 5.6382 0.1455
NCI-H520 GDSC2; CTRP2 7.8987 11.1378 4.8266 2.3037
DMS 273 GDSC2; CTRP2 7.9084 9.4159 5.5465 0.2742
LC-1/sq-SF CTRP2 7.9546 9.0986 5.6769 0.0874
IA-LM GDSC2; CTRP2 7.9602 9.2385 5.6304 0.1325
NCI-H1355 GDSC2; CTRP2 7.9637 11.2595 4.8093 2.2995
SK-MES-1 GDSC2; CTRP2 7.9676 10.4735 5.1528 1.2106
NCI-H2172 GDSC2; CTRP2 7.9954 9.3257 5.6128 0.1478
HCC1195 CTRP2 8.0107 9.4361 5.5793 0.2037
NCI-H1755 GDSC2; CTRP2 8.1403 10.193 5.3486 0.5884
SK-LU-1 GDSC2; CTRP2 8.1796 9.7138 5.5442 0.2002
RERF-LC-Ad2 CTRP2 8.1976 10.6679 5.1852 1.0293
NCI-H460 GDSC2; CTRP2 8.2295 9.3615 5.6836 0.046
Calu-6 GDSC2; CTRP2 8.3274 9.8384 5.5554 0.1525
NCI-H1650 GDSC2; CTRP2 8.3789 11.4284 4.9589 1.4789
NCI-H1339 CTRP2 8.396 11.6307 4.882 1.8081
LXF 289 GDSC2; CTRP2 8.4062 10.0237 5.5194 0.1822
HCC1438 CTRP2 8.408 9.7787 5.605 0.093
NCI-H441 GDSC2; CTRP2 8.4253 10.2753 5.4363 0.3022
NCI-H1184 CTRP2 8.4437 10.322 5.4264 0.334
NCI-H322 CTRP2 8.4743 10.3767 5.4185 0.3383
NCI-H1651 GDSC2; CTRP2 8.4758 10.5428 5.3575 0.4272
NCI-H2122 GDSC2; CTRP2 8.4785 9.8261 5.6135 0.0717
RERF-LC-MS GDSC2; CTRP2 8.5032 10.1065 5.5261 0.1542
DMS 114 GDSC2; CTRP2 8.5406 9.8434 5.629 0.0546
NCI-H2023 GDSC2; CTRP2 8.5902 10.0574 5.5742 0.0912
COR-L105 GDSC2; CTRP2 8.5967 12.9719 4.4054 3.0455
PC-14 GDSC2; CTRP2 8.633 10.209 5.5376 0.1197
NCI-H1869 GDSC2; CTRP2 8.7212 10.3882 5.5074 0.1371
SW1271 GDSC2; CTRP2 8.7306 10.4989 5.4724 0.1754
EBC-1 GDSC2; CTRP2 8.7348 10.2917 5.5454 0.0982
NCI-H1623 GDSC2; CTRP2 8.7437 11.0427 5.2802 0.4775
NCI-H1792 GDSC2; CTRP2 8.8018 10.8108 5.3885 0.2733
NCI-H2342 GDSC2; CTRP2 8.8086 11.1928 5.2506 0.5108
LCLC-97TM1 GDSC2; CTRP2 8.8427 10.5274 5.503 0.123
NCI-H1373 CTRP2 8.8585 10.5325 5.5069 0.1248
HOP-92 GDSC2; CTRP2 8.8723 11.5432 5.1439 0.7074
Calu-1 CTRP2 8.9024 10.475 5.5417 0.0871
NCI-H446 GDSC2; CTRP2 9.332 24.4917 -0.6035 18.2644
Lu-65 GDSC2; CTRP2 9.9851 22.5684 0.7911 13.483
Hs 888.Lu CTRP2 8.4516 14.3786 3.672 6.1423
⏷ Show the Full List of 201 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Lymphoma Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
CBTCi002-A GDSC2 2.9401 4.7814 -0.5933 0.2481
Cancer Drug Sensitivity Data Curated from 2 Cell Line(s) in Thigh Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
P-STS CTRP2 7.1762 22.8893 -1.4544 24.661
SYO-1 CTRP2 7.8 12.6058 4.0861 5.3886
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Clivus Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
U-CH1 CTRP2 7.9161 9.9438 5.3459 0.7601
Cancer Drug Sensitivity Data Curated from 38 Cell Line(s) in Ovary Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
2004 CTRP2 8.4465 11.012 5.1627 0.9356
OVCAR-3 GDSC2 1.2247 3.8878 -1.0428 3.7749
OVKATE GDSC2 1.6065 10.0709 -3.7674 17.6983
ES-2 GDSC2 1.6302 3.5416 -0.6673 1.2468
OVISE GDSC2 1.7563 9.4049 -3.3313 15.3169
TOV-21G GDSC2 1.8233 3.01 -0.3835 0.1822
JHOS-4 GDSC2 1.8745 4.7636 -1.0606 2.8405
DOV13 GDSC2 1.8821 3.5355 -0.5518 0.595
Kuramochi GDSC2 1.8924 4.621 -0.9892 2.4553
Caov-4 GDSC2 2.0512 7.3938 -2.1591 8.5568
TOV-112D GDSC2 2.059 4.0533 -0.6749 0.8968
OVTOKO GDSC2 2.5554 4.6546 -0.6946 0.639
OVCAR-5 GDSC2; CTRP2 2.6119 3.2248 2.6119 21.4405
OC 314 GDSC2; CTRP2 2.6358 3.0773 2.6358 21.2915
TYK-nu GDSC2; CTRP2 3.1192 4.5683 3.1038 18.3202
A2780 GDSC2; CTRP2 3.6276 5.6124 3.511 15.4718
OV7 CTRP2 3.6433 7.0415 3.0972 17.9722
OAW42 GDSC2; CTRP2 4.0602 5.6425 3.974 12.6712
COV362 CTRP2 4.2718 22.0912 -3.5003 37.7605
EFO-27 GDSC2; CTRP2 5.931 7.7768 5.0819 4.0034
OV-90 GDSC2; CTRP2 7.6533 10.0479 5.1711 1.401
OV56 GDSC2; CTRP2 7.7624 8.798 5.7116 0.0759
Caov-3 GDSC2; CTRP2 7.8948 9.3868 5.5518 0.2693
HEY A8 CTRP2 8.0072 9.1119 5.6909 0.0669
SK-OV-3 GDSC2; CTRP2 8.1525 9.5742 5.5836 0.1526
FU-OV-1 GDSC2; CTRP2 8.2157 10.2036 5.3772 0.4907
JHOS-2 GDSC2; CTRP2 8.2254 9.9731 5.4678 0.3102
OVK18 GDSC2; CTRP2 8.2275 9.7626 5.545 0.1877
EFO-21 GDSC2; CTRP2 8.3768 9.9908 5.52 0.1878
JHOM-1 CTRP2 8.4713 10.3794 5.4163 0.3433
MCAS CTRP2 8.622 9.9791 5.6115 0.0629
IGROV-1 GDSC2; CTRP2 8.6427 10.3907 5.4779 0.1861
OAW28 GDSC2; CTRP2 8.6537 11.2221 5.1731 0.7442
RMG-I GDSC2; CTRP2 8.6854 10.5559 5.4354 0.2338
OVCAR-4 GDSC2; CTRP2 9.0463 10.8957 5.4492 0.1465
OVCAR-8 GDSC2; CTRP2 9.0605 10.6921 5.5233 0.0792
SNU-840 CTRP2 10.0038 18.8458 2.5654 8.2759
COV644 CTRP2 13.1981 29.9851 -0.6189 14.113
⏷ Show the Full List of 38 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 28 Cell Line(s) in Soft Tissue Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
Yamato-SS CTRP2 9.141 24.9029 -0.9451 20.2321
VA-ES-BJ GDSC2 1.1933 2.885 -0.6114 1.4874
EW-8 GDSC2 1.3518 3.1951 -0.6613 1.5322
SW684 GDSC2 1.411 3.0632 -0.5767 1.0751
Rh18 CTRP2 1.4904 8.0635 0.407 33.6773
Hs 633.T GDSC2 1.6352 3.4407 -0.6239 1.0565
SW872 GDSC2 1.7217 4.372 -0.9727 2.6024
G-401 GDSC2 1.9332 6.174 -1.6632 6.0182
HT-1080 GDSC2 2.0232 3.6502 -0.537 0.4685
Rh30 GDSC2 2.0743 5.7653 -1.3925 4.291
TE 441.T GDSC2; CTRP2 2.2101 7.797 1.2782 26.9943
MFH-ino GDSC2 2.2392 4.1351 -0.6297 0.6233
STS-0421 GDSC2 2.3259 4.5379 -0.7466 0.9557
Rh41 GDSC2 3.0211 21.0431 -8.1221 27.9122
GCT GDSC2; CTRP2 4.2614 6.8035 3.849 12.5391
A-204 GDSC2; CTRP2 4.307 5.9183 4.1813 11.2617
MES-SA GDSC2; CTRP2 5.3299 9.3686 3.7549 10.4022
KYM-1 GDSC2; CTRP2 6.8031 12.7482 3.3019 9.4763
BT-12 CTRP2 6.8279 7.6632 5.7574 0.3036
BT-16 CTRP2 7.5515 8.9327 5.5807 0.3645
Tm87-16 CTRP2 7.606 9.0353 5.5647 0.3761
SW982 GDSC2; CTRP2 7.864 9.2186 5.6012 0.1962
SK-LMS-1 GDSC2; CTRP2 8.1165 14.1191 3.576 6.5327
RKN GDSC2; CTRP2 8.2579 9.3236 5.7057 0.0314
TTC-709 CTRP2 8.3691 9.7709 5.5939 0.1097
G-402 GDSC2; CTRP2 8.8724 13.7169 4.2299 3.3679
RD GDSC2; CTRP2 11.3335 22.4923 1.6988 9.1142
SK-UT-1 GDSC2; CTRP2 14.5631 27.9748 1.1008 7.7576
⏷ Show the Full List of 28 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Pleura Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H28 GDSC2 1.7267 5.7887 -1.6131 6.1157
MPP 89 GDSC2; CTRP2 8.0503 9.6631 5.5121 0.2889
IST-Mes1 GDSC2; CTRP2 8.1464 9.8489 5.482 0.311
NCI-H2052 GDSC2; CTRP2 8.1814 10.4553 5.2635 0.7718
JL-1 CTRP2 8.1859 9.432 5.6448 0.0856
MSTO-211H GDSC2; CTRP2 8.3091 10.0935 5.4569 0.3028
NCI-H2452 GDSC2; CTRP2 8.7183 10.7872 5.3646 0.3341
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 7 Cell Line(s) in Prostate Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
NCI-H660 GDSC2; CTRP2 -1.1138 1.8854 -1.1281 44.744
LNCaP clone FGC GDSC2 0.876 3.505 -1.0872 4.7133
PC-3 GDSC2 1.6429 5.929 -1.7326 6.961
22Rv1 GDSC2 3.0537 5.1099 -0.6664 0.3527
PaCa-3 CTRP2 7.7331 10.3941 5.0634 1.7875
VCaP GDSC2; CTRP2 8.1421 15.5623 2.8999 8.9729
DU145 GDSC2; CTRP2 8.5955 10.7733 5.3203 0.455
⏷ Show the Full List of 7 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Salivary Gland Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
A-253 GDSC2; CTRP2 4.3528 7.6063 3.622 13.1271
Cancer Drug Sensitivity Data Curated from 1 Cell Line(s) in Small Intestine Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
HuTu 80 GDSC2 0.9528 3.3058 -0.9424 3.6981
Cancer Drug Sensitivity Data Curated from 36 Cell Line(s) in Stomach Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
ECC10 GDSC2; CTRP2 -1.4636 3.7475 -1.6557 47.1041
SNU-16 GDSC2 0.3311 2.0092 -0.7438 3.8297
AGS GDSC2 0.7735 2.5452 -0.7002 2.6246
ECC12 GDSC2 0.9823 10.6252 -4.5178 22.3802
MKN45 GDSC2 1.0777 2.8075 -0.64 1.7906
SCH GDSC2 1.1143 9.055 -3.6357 18.3234
GCIY GDSC2 1.1633 4.1948 -1.2252 4.9514
SNU-5 GDSC2 1.3111 3.2843 -0.7212 1.8823
23132/87 GDSC2 1.5073 5.4737 -1.6057 6.4971
NCI-N87 GDSC2 1.5585 11.4142 -4.4661 20.734
MKN1 GDSC2 1.6726 3.1915 -0.5092 0.5912
TMK-1 GDSC2 1.7809 3.9309 -0.7544 1.4743
RERF-GC-1B GDSC2 1.8471 7.9654 -2.5683 11.2115
TGBC11TKB GDSC2 1.854 4.273 -0.8609 1.8811
NUGC-4 GDSC2 1.8708 3.9002 -0.6992 1.1485
HSC-39 GDSC2 1.9448 3.4601 -0.4983 0.4007
RF-48 GDSC2 2.203 4.1907 -0.6658 0.7622
SK-GT-2 GDSC2 2.4653 4.921 -0.8346 1.172
MKN28 GDSC2 2.6816 11.1164 -3.5134 14.1476
HGC-27 GDSC2; CTRP2 3.3889 5.3204 3.3071 16.8485
KE-39 CTRP2 4.6969 8.0394 3.7819 12.4752
Hs 746.T GDSC2; CTRP2 5.1943 6.4959 4.9635 6.1005
SNU-1 GDSC2; CTRP2 6.5641 14.4901 2.2465 13.8238
Fu97 GDSC2; CTRP2 7.5192 9.3714 5.3898 0.844
SNU-601 CTRP2 7.9217 9.465 5.5337 0.3125
SH-10-TC CTRP2 7.9748 9.1653 5.6612 0.1009
NUGC-3 GDSC2; CTRP2 8.2323 9.7385 5.5553 0.1725
MKN7 GDSC2; CTRP2 8.2398 11.3274 4.9303 1.6706
OCUM-1 GDSC2; CTRP2 8.2841 10.2696 5.3809 0.4546
SNU-216 CTRP2 8.308 9.7032 5.5953 0.118
KATO III GDSC2; CTRP2 8.3806 10.1342 5.4701 0.2601
MKN74 CTRP2 9.1305 11.0313 5.4326 0.1605
IM95 GDSC2; CTRP2 10.9678 25.2623 0.164 14.0372
LMSU CTRP2 11.7496 20.7337 2.7327 5.8585
SNG-M GDSC2; CTRP2 8.2148 9.6712 5.5725 0.1538
SNU-685 CTRP2 8.2839 9.5475 5.6399 0.0772
⏷ Show the Full List of 36 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 17 Cell Line(s) in Thyroid Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
IHH-4 GDSC2 0.6639 2.8759 -0.9293 4.2106
TT GDSC2 1.1704 4.6871 -1.4545 6.2955
CAL-62 GDSC2 1.4153 2.8903 -0.5049 0.7721
8305C GDSC2 1.431 5.7924 -1.8079 7.8299
CGTH-W-1 GDSC2 1.4761 3.1737 -0.5907 1.0701
WRO GDSC2 1.4847 3.4009 -0.6805 1.465
KMH-2 GDSC2 1.7906 4.1551 -0.8433 1.8728
HTC-C3 GDSC2 1.8605 6.9287 -2.0635 8.4057
K5 GDSC2 1.9107 3.5765 -0.5554 0.5887
B-CPAP GDSC2 2.1362 6.8154 -1.8347 6.604
TT2609-C02 GDSC2 2.3547 4.6702 -0.7854 1.0754
ASH-3 GDSC2 2.425 3.7514 -0.4239 0.1081
BHT-101 GDSC2 2.8105 13.8791 -4.7597 19.0281
8505C GDSC2 3.6857 14.3635 -4.3911 15.8813
ML-1 [Human leukemia] GDSC2; CTRP2 5.6738 7.03 5.2167 4.0009
FTC-238 CTRP2 8.2133 9.469 5.6419 0.0846
FTC-133 GDSC2; CTRP2 8.3657 22.4538 -0.3153 18.9308
⏷ Show the Full List of 17 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 47 Cell Line(s) in Upper Aerodigestive Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BHY GDSC2 1.382 3.2153 -0.6544 1.4623
SCC-15 GDSC2 1.4287 7.5779 -2.6743 12.728
KON GDSC2 1.4605 5.007 -1.4162 5.4897
OSC-19 GDSC2 1.5133 3.7205 -0.8019 2.0184
JHU-011 GDSC2 1.5337 12.0984 -4.8234 22.1364
SCC-4 GDSC2 1.5776 5.1049 -1.3881 5.1097
PCI-30 GDSC2 1.655 5.4657 -1.5075 5.648
PCI-06A GDSC2 1.6999 11.5829 -4.443 20.3042
JHU-029 GDSC2 1.7975 4.1154 -0.8231 1.7697
KOSC-2 GDSC2 1.8848 5.4241 -1.3489 4.3587
PCI-15A GDSC2 1.9086 3.5702 -0.5539 0.5852
UPCI-SCC-090 GDSC2 1.9697 12.9896 -4.9352 21.5103
HO-1-N-1 GDSC2 1.9702 4.335 -0.829 1.6058
BICR 78 GDSC2 1.9874 6.1469 -1.6175 5.6668
SKN-3 GDSC2 2.0095 4.4153 -0.843 1.6265
BB30-HNC GDSC2 2.0594 5.3126 -1.1999 3.2973
Ca9-22 GDSC2 2.1193 7.4409 -2.1373 8.3036
OSC-20 GDSC2 2.2352 4.5674 -0.7985 1.2236
SAS GDSC2 2.2476 4.6846 -0.8396 1.3778
HSC-3 GDSC2 2.2493 3.8645 -0.5266 0.338
Detroit 562 GDSC2 2.2635 4.0823 -0.6002 0.5225
JHU-022 GDSC2 2.2879 7.7214 -2.1613 8.1128
BB49-HNC GDSC2 2.359 13.8917 -5.0914 21.1848
HO-1-u-1 GDSC2 2.3973 4.1405 -0.569 0.3787
BICR 10 GDSC2 2.4248 4.312 -0.6205 0.4974
NCI-H3118 GDSC2 2.4873 4.7791 -0.77 0.9223
HSC-2 GDSC2; CTRP2 2.4973 3.0311 2.4973 22.1562
PE/CA-PJ15 GDSC2 2.5096 4.1879 -0.5436 0.2816
DOK GDSC2 2.5208 5.1207 -0.8885 1.3327
LB771-HNC GDSC2 2.5473 11.8617 -3.9655 16.4308
PCI-04B GDSC2 2.6847 4.7712 -0.6859 0.5478
SAT [Human HNSCC] GDSC2 2.709 6.7616 -1.4794 3.8155
FaDu GDSC2; CTRP2 3.6416 5.3247 3.5778 15.2121
HSC-4 GDSC2; CTRP2 3.6516 5.7023 3.5179 15.3784
PE/CA-PJ34 (clone C12) CTRP2 6.0741 10.7028 3.7399 9.6182
PE/CA-PJ41 (clone D2) CTRP2 6.2952 12.2865 3.1298 11.708
BICR 6 CTRP2 7.5372 8.8311 5.6133 0.2993
BICR 16 CTRP2 7.6672 9.2159 5.5214 0.4477
SCC-25 GDSC2; CTRP2 7.795 11.5689 4.5689 3.3055
CAL-27 GDSC2; CTRP2 7.8501 9.0901 5.6418 0.1409
YD-8 CTRP2 8.0703 10.2351 5.3004 0.7902
BICR 56 CTRP2 8.0935 9.7776 5.4871 0.3408
BICR 22 GDSC2; CTRP2 8.3023 9.6651 5.6064 0.1003
BICR 18 CTRP2 8.3041 10.0871 5.4572 0.3239
BICR 31 GDSC2; CTRP2 8.3167 10.6859 5.2334 0.7727
SCC-9 GDSC2; CTRP2 8.4176 10.335 5.4112 0.3479
CAL-33 GDSC2; CTRP2 8.745 10.6 5.4422 0.2109
⏷ Show the Full List of 47 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 20 Cell Line(s) in Urinary Tract Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
BFTC-905 GDSC2 1.1026 5.0607 -1.6807 7.7925
SW780 GDSC2 1.1245 5.8791 -2.0632 10.0055
KU-19-19 GDSC2 1.2876 9.1132 -3.533 17.4077
CAL-29 GDSC2 1.4807 3.0306 -0.5309 0.8185
639V GDSC2 1.648 2.9757 -0.4383 0.3841
TCCSUP GDSC2 1.9253 5.0974 -1.1794 3.3849
SW1710 GDSC2 1.9464 5.9107 -1.5339 5.2744
5637 GDSC2 2.3527 5.8545 -1.2771 3.2843
HT-1197 GDSC2; CTRP2 3.8149 5.7717 3.68 14.3634
BC-3C CTRP2 4.5101 6.8422 4.1004 11.7174
T24 GDSC2; CTRP2 4.5258 7.4275 3.8779 11.7548
KMBC-2 CTRP2 4.7109 7.0974 4.21 10.7429
U-BLC1 CTRP2 6.1734 11.18 3.5833 10.0788
RT-112 GDSC2; CTRP2 7.7093 13.904 3.4008 7.7303
RT-4 GDSC2; CTRP2 8.1529 9.7922 5.5055 0.2682
SCaBER CTRP2 8.2819 9.4464 5.6732 0.0514
647V GDSC2; CTRP2 8.4224 9.5703 5.6795 0.0342
HT-1376 GDSC2; CTRP2 8.6198 10.5155 5.4249 0.2657
UM-UC-3 GDSC2; CTRP2 9.7157 16.7009 3.3757 5.3987
J82 GDSC2; CTRP2 11.8007 21.9363 2.2282 7.0165
⏷ Show the Full List of 20 Cancer Drug Sensitivity Data of This Drug
Cancer Drug Sensitivity Data Curated from 39 Cell Line(s) in Urogenital System Tissue
Cell Line Original Dataset IC50 IC90 EC50 AUC
TC-YIK GDSC2 0.4765 12.2914 -5.7533 27.832
NCC-IT GDSC2 0.5456 2.2678 -0.7177 3.1812
NT2-D1 GDSC2 0.6884 4.1293 -1.5228 7.7983
OVCA420 GDSC2 0.9699 6.3274 -2.3963 12.3005
OVCA433 GDSC2 1.2235 3.3492 -0.7983 2.4143
SW962 GDSC2 1.2255 5.6062 -1.8591 8.5765
HEC-1 GDSC2 1.2274 2.8788 -0.591 1.3456
NEC8 GDSC2 1.2309 3.3386 -0.7894 2.3546
PA-1 GDSC2 1.2894 9.5031 -3.7244 18.2838
LB831-BLC GDSC2 1.301 6.7435 -2.3586 11.2873
DoTc2 4510 GDSC2 1.3437 3.6706 -0.8733 2.6328
SW954 GDSC2 1.4516 4.0402 -0.977 3.0249
SW756 GDSC2 1.4967 9.3193 -3.4787 16.6374
C-33 A GDSC2 1.516 3.9344 -0.8937 2.4843
OVMIU GDSC2 1.5162 4.7722 -1.2721 4.5602
DSH1 GDSC2 1.5896 4.0318 -0.896 2.3925
UWB1.289 GDSC2 1.6645 4.4156 -1.0235 2.9488
SiHa GDSC2 1.6886 3.2239 -0.5148 0.5992
PWR-1E GDSC2 1.7456 5.8433 -1.6266 6.1575
HT-3 GDSC2 1.8019 9.0037 -3.1028 14.0893
JEG-3 GDSC2 1.8313 9.3426 -3.247 14.735
C-4-I GDSC2 1.8572 5.32 -1.3179 4.2344
JAR GDSC2 1.9394 3.6869 -0.5853 0.668
SKG-IIIa GDSC2 2.0198 4.2364 -0.7652 1.2822
PEO1 GDSC2 2.049 6.839 -1.9 7.1262
SKN GDSC2 2.0563 6.9441 -1.9445 7.3597
HEY GDSC2 2.1833 4.4919 -0.7921 1.2435
KGN GDSC2 2.2118 7.3676 -2.0441 7.6168
BPH-1 GDSC2 2.3381 10.3569 -3.3831 14.2644
JHOS-3 GDSC2 2.348 4.2611 -0.6324 0.5702
CAL-39 GDSC2 2.3732 4.2937 -0.6343 0.5622
SiSo GDSC2 2.4261 4.7178 -0.7727 0.9754
Ca Ski GDSC2 2.5739 5.829 -1.1518 2.4069
OMC-1 [Human cervical carcinoma] GDSC2 2.6725 4.507 -0.5956 0.3345
MS751 GDSC2 2.7204 14.358 -5.0574 20.288
ACC-OV7 GDSC2 2.8409 5.473 -0.885 1.0724
ME-180 GDSC2 3.2735 13.9852 -4.4884 17.0579
OV17R GDSC2 3.6125 5.818 -0.7094 0.2718
HeLa GDSC2; CTRP2 7.3435 8.2998 5.7319 0.134
⏷ Show the Full List of 39 Cancer Drug Sensitivity Data of This Drug

References

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